Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.43 |
| ▸ | CES2 | O00748 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2909086 | 0.86 | MAPT (0.35) | TSHRMAPTHSD17B10HTT | |
| SCHEMBL4176133 | 0.82 | TDP1 (0.41) | CES1CES2TDP1CA2HSD17B10 | |
| SCHEMBL11223783 | 0.80 | CES1 (0.40) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL9119892 | 0.78 | MAPT (0.42) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL535862 | 0.78 | CES1 (0.48) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL9554891 | 0.75 | CES2 (0.48) | CES1CES2ALDH1A1TSHRMAPT | |
| SCHEMBL334045 | 0.75 | NAPRT (0.46) | ALDH1A1NAPRTLMNACYP3A4SMN1; SMN2 | |
| SCHEMBL8466980 | 0.75 | AKT1 (0.43) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL330617 | 0.74 | ALDH1A1 (0.42) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL6865935 | 0.74 | MAOA (0.41) | CES1CES2ALDH1A1TSHRDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1250 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117886839-A | Organic semiconductor luminescent compound and application thereof | 冠能光电材料(深圳)有限责任公司 | 2024-04-16 | — | — | CN | claimed |
| US-11827786-B2 | Resin composition and article made therefrom | ELITE ELECTRONIC MATERIAL (KUNSHAN) CO., LTD. (CN) | 2023-11-28 | — | — | US | claimed |
| US-20230151213-A1 | RESIN COMPOSITION AND ARTICLE MADE THEREFROM | ELITE ELECTRONIC MATERIAL (KUNSHAN) CO., LTD. (CN) | 2023-05-18 | — | — | US | claimed |
| CN-115433203-A | Amine fluorinated curcumenol derivative compound and application and preparation method thereof | 华东理工大学 | 2022-12-06 | — | — | CN | claimed |
| CN-114773237-A | Novel phenylpropenyl hydroximic acid derivatives containing sulfonate structure, and preparation method and application thereof | 南京大学 | 2022-07-22 | — | — | CN | claimed |
| EP-3268375-B1 | PHOTOCHROMIC THIENOCHROMENE COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2022-06-15 | — | — | EP | claimed |
| EP-3071576-B9 | PHOTOCHROMIC INDENO-FUSED RING PYRAN COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2021-12-22 | — | — | EP | claimed |
| EP-3645540-B1 | SILOLE AND GERMOLE FUSED RING PHOTOCHROMIC COMPOUNDS | TRANSITIONS OPTICAL LTD (IE) | 2021-11-03 | — | — | EP | claimed |
| CN-113387831-A | Amide compound and application thereof in preparation of neuroinflammation inhibitor | 苏州大学 | 2021-09-14 | — | — | CN | claimed |
| EP-3071576-B1 | PHOTOCHROMIC INDENO-FUSED RING PYRAN COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2021-08-18 | — | — | EP | claimed |
| US-20040014796-A1 | Novel compounds and compositions as cathepsin S inhititors | AXYS PHARMACEUTICALS, INC. | 2004-01-22 | — | — | US | claimed |
| US-6492362-B1 | Compounds and compositions as cathepsin S inhibitors | AXYS PHARMACEUTICALS, INC. | 2002-12-10 | — | — | US | claimed |
| CN-1082993-C | Optically active smectic photo-cross-linkable liquid crystals | ROLIC AG (CH) | 2002-04-17 | — | — | CN | claimed |
| WO-2001019808-A1 | CHEMICAL COMPOUNDS AND COMPOSITIONS AND THEIR USE AS CATHEPSIN S INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-03-22 | — | — | WO | claimed |
| CN-1126748-A | Optically active smectic photo-cross-linkable liquid crystals | HOFFMANN LA ROCHE (CH) | 1996-07-17 | — | — | CN | claimed |
| US-5250498-A | Applying to weeds | BAYER AKTIENGESELLSCHAFT (DE) | 1993-10-05 | — | — | US | claimed |
| EP-0432600-A2 | Derivatives of 2-iminopyridine | BAYER AG (DE) | 1991-06-19 | — | — | EP | claimed |
| US-4981847-A | Tricyclic compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-01-01 | — | — | US | claimed |
| US-4578469-A | COUMARIN DYES | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-03-25 | — | — | US | claimed |
| US-4433152-A | ANTIINFLAMMATORY AGENT, ANTIALLERGEN OR ANTICOAGULANT | NIPPON CHEMIPHAR CO., LTD. (JP) | 1984-02-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014796-A1 | Novel compounds and compositions as cathepsin S inhititors | CTSS, CTSB, CTSE | CES1 279/4885CES2 480/4885ALDH1A1 4044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.