Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14980681 | 0.81 | CYP1A2 (0.32) | ACHECYP1A2CYP2C19MEN1ALDH1A1 | |
| SCHEMBL14980641 | 0.72 | MEN1 (0.31) | MEN1ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL13174918 | 0.70 | ALDH1A1 (0.38) | MEN1ALDH1A1 | |
| SCHEMBL14980671 | 0.64 | USP2 (0.37) | CYP1A2MEN1ALDH1A1 | |
| SCHEMBL24525736 | 0.64 | GAA (0.36) | MEN1ALDH1A1RAB9A | |
| SCHEMBL14980658 | 0.62 | CYP1A2 (0.38) | CYP1A2MEN1ALDH1A1RAB9A | |
| SCHEMBL14981115 | 0.62 | NTRK1 (0.33) | RAB9A | |
| SCHEMBL14981221 | 0.62 | MTNR1A (0.31) | — | |
| SCHEMBL1760852 | 0.62 | BAZ2B (0.44) | ACHECYP1A2CYP2C19ALDH1A1RAB9A | |
| SCHEMBL24525789 | 0.62 | GAA (0.35) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411396-B1 | THIENOPYRIMIDINEDIONE DERIVATIVES AS TRPA1 MODULATORS | GLENMARK PHARMACEUTICALS SA (CH) | 2013-05-29 | — | — | EP | disclosed |