Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14980935 | 0.85 | PLK1 (0.44) | ALDH1A1SLC6A3LMNAMAPTKMT2A | |
| SCHEMBL13871145 | 0.84 | CNR2 (0.39) | ALDH1A1CCR1CNR2CNR1LMNA | |
| SCHEMBL3314911 | 0.84 | CNR2 (0.41) | ALDH1A1CCR1CNR2CNR1LMNA | |
| SCHEMBL31253337 | 0.84 | CNR2 (0.44) | ALDH1A1CCR1CNR2CNR1LMNA | |
| SCHEMBL3315068 | 0.83 | CYP1A2 (0.43) | ALDH1A1SLC6A3CCR1CNR2CNR1 | |
| SCHEMBL6268395 | 0.83 | CNR2 (0.39) | ALDH1A1CCR1CNR2CNR1LMNA | |
| SCHEMBL3314780 | 0.81 | FKBP1A (0.42) | ALDH1A1SMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL14980957 | 0.81 | CNR2 (0.39) | ALDH1A1CNR2CNR1LMNAMAPT | |
| SCHEMBL3314415 | 0.77 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2SLC6A3MAPTKMT2A | |
| SCHEMBL13398105 | 0.77 | OPRM1 (0.39) | ALDH1A1CNR2CNR1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9199934-B2 | Alpha-hydroxyketones | BASF SE (DE) | 2015-12-01 | — | — | US | disclosed |
| EP-2129659-B1 | ALPHA-HYDROXYKETONES | BASF SE (DE) | 2013-05-29 | — | — | EP | disclosed |