SCHEMBL1498097

SCHEMBL1498097

O=C(O)c1ccc(N=Nc2ccc(C(=O)O)c(Cl)c2)cc1Cl

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
CASP1 P29466 1/20 0.61
MEN1 O00255 5/20 0.57
KMT2A Q03164 5/20 0.57
HTT P42858 2/20 0.57
PDE4A P27815 1/20 0.57
BLVRB P30043 1/20 0.57
KDR P35968 1/20 0.57
TDP1 Q9NUW8 2/20 0.50
APP P05067 1/20 0.50
THRB P10828 1/20 0.50
RECQL P46063 1/20 0.50
BLM P54132 1/20 0.50
ALDH1A1 P00352 6/20 0.48
MYC P01106 1/20 0.47
NR4A1 P22736 1/20 0.47
CYP2C19 P33261 3/20 0.46
MAPT P10636 2/20 0.46
TP53 P04637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1498095 1.00 TSHR (0.61) TSHRSMN1; SMN2CASP1MEN1KMT2A
SCHEMBL3708846 0.88 TSHR (0.58) TSHRSMN1; SMN2CASP1MEN1KMT2A
SCHEMBL3396994 0.83 TSHR (0.52) TSHRSMN1; SMN2CASP1MEN1KMT2A
SCHEMBL10478148 0.83 MEN1 (0.43) TSHRSMN1; SMN2CASP1MEN1KMT2A
SCHEMBL10961676 0.83 MEN1 (0.62) TSHRSMN1; SMN2CASP1MEN1KMT2A
SCHEMBL1602880 0.80 MEN1 (0.69) TSHRSMN1; SMN2MEN1KMT2AHTT
SCHEMBL30221905 0.80 MEN1 (0.69) TSHRSMN1; SMN2MEN1KMT2AHTT
SCHEMBL830090 0.80 MEN1 (0.69) TSHRSMN1; SMN2MEN1KMT2AHTT
SCHEMBL28234558 0.80 MEN1 (0.55) SMN1; SMN2MEN1KMT2AHTTPDE4A
SCHEMBL31010511 0.80 TSHR (0.52) TSHRSMN1; SMN2CASP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023104665-A1 METAL ORGANIC FRAMEWORKS FOR THE SELECTIVE CAPTURE OF VOLATIL ORGANIC COMPOUNDS COMPRISING CARBOXYLIC ACID FUNCTIONAL GROUP(S) AND/OR VOLATILE ALCOHOLS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2023-06-15 WO claimed
EP-4194084-A1 METAL ORGANIC FRAMEWORKS FOR THE SELECTIVE CAPTURE OF VOLATIL ORGANIC COMPOUNDS COMPRISING CARBOXYLIC ACID FUNCTIONAL GROUP(S) Centre National de la Recherche Scientifique (FR) 2023-06-14 EP claimed
CN-114903028-A Erythrocyte cryoprotectant and preparation method and application thereof 华南理工大学 2022-08-16 CN claimed
US-20210277042-A1 LOW TEMPERATURE PROCESS FOR THE SYNTHESIS OF MOF CARBOXYLATE NANOPARTICLES UNIVERSITÉ DE VERSAILLES - SAINT-QUENTIN-EN-YVELINES (FR) 2021-09-09 US claimed
US-11034711-B2 Low temperature process for the synthesis of MOF carboxylate nanoparticles CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2021-06-15 US claimed
EP-3357929-B1 LOW TEMPERATURE PROCESS FOR THE SYNTHESIS OF MOF CARBOXYLATE NANOPARTICLES CENTRE NAT RECH SCIENT (FR) 2020-06-17 EP claimed
US-20200102337-A1 LOW TEMPERATURE PROCESS FOR THE SYNTHESIS OF MOF CARBOXYLATE NANOPARTICLES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2020-04-02 US claimed
US-10159738-B2 Organic-inorganic hybrid solid having a modified outer surface CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) 2018-12-25 US claimed
US-20180346500-A1 ORGANIC/INORGANIC HYBRID NANOPARTICULATES MADE FROM IRON CARBOXYLATES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2018-12-06 US claimed
US-10065979-B2 Organic/inorganic hybrid nanoparticulates made from iron carboxylates CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) 2018-09-04 US claimed
WO-2018141685-A1 LOW TEMPERATURE PROCESS FOR THE SYNTHESIS OF MOF CARBOXYLATE NANOPARTICLES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2018-08-09 WO claimed
EP-3357929-A1 LOW TEMPERATURE PROCESS FOR THE SYNTHESIS OF MOF CARBOXYLATE NANOPARTICLES Centre National De La Recherche Scientifique (FR) 2018-08-08 EP claimed
EP-2855490-B1 IMPROVED ORGANIC-INORGANIC HYBRID SOLID HAVING A MODIFIED OUTER SURFACE CENTRE NATIONAL DE LA RECHERCHE SCIENT (C N R S ) (FR) 2018-03-07 EP claimed
US-20150150981-A1 ORGANIC-INORGANIC HYBRID SOLID HAVING A MODIFIED OUTER SURFACE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) 2015-06-04 US claimed
EP-2193136-B1 SOLID INORGANIC/ORGANIC HYBRID WITH MODIFIED SURFACE CENTRE NAT RECH SCIENT (FR) 2014-07-30 EP claimed
EP-2193137-B1 ORGANIC/INORGANIC HYBRID NANOPARTICULATES MADE FROM IRON CARBOXYLATES CENTRE NAT RECH SCIENT (FR) 2013-07-10 EP claimed
US-20100226991-A1 SOLID INORGANIC/ORGANIC HYBRID WITH MODIFIED SURFACE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS- (FR) 2010-09-09 US claimed
US-20100209354-A1 ORGANIC/INORGANIC HYBRID NANOPARTICULATES MADE FROM IRON CARBOXYLATES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) 2010-08-19 US claimed
US-11739112-B2 Low temperature process for the synthesis of MOF carboxylate nanoparticles CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2023-08-29 US disclosed
US-20100209354-A1 ORGANIC/INORGANIC HYBRID NANOPARTICULATES MADE FROM IRON CARBOXYLATES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) 2010-08-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200102337-A1 LOW TEMPERATURE PROCESS FOR THE SYNTHESIS OF MOF CARBOXYLATE NANOPARTICLES FTO, TPI1, ACP1 TSHR 3308/4885SMN1; SMN2 4546/4885CASP1 3961/4885
US-10159738-B2 Organic-inorganic hybrid solid having a modified outer surface SLCO4C1, SLCO2A1, SLCO1A2 TSHR 1448/4885SMN1; SMN2 1477/4885CASP1 4686/4885
US-20100226991-A1 SOLID INORGANIC/ORGANIC HYBRID WITH MODIFIED SURFACE SLCO2A1, SLCO4C1, SLCO2B1 TSHR 1720/4885SMN1; SMN2 3720/4885CASP1 4773/4885
US-20150150981-A1 ORGANIC-INORGANIC HYBRID SOLID HAVING A MODIFIED OUTER SURFACE SLCO4C1, SLCO2A1, SLCO1A2 TSHR 1448/4885SMN1; SMN2 1477/4885CASP1 4686/4885
US-10065979-B2 Organic/inorganic hybrid nanoparticulates made from iron carboxylates SLC39A3, SLC40A1, AOC3 TSHR 2404/4885SMN1; SMN2 4486/4885CASP1 4075/4885
US-20210277042-A1 LOW TEMPERATURE PROCESS FOR THE SYNTHESIS OF MOF CARBOXYLATE NANOPARTICLES FTO, TPI1, ACP1 TSHR 3308/4885SMN1; SMN2 4546/4885CASP1 3961/4885
US-20180346500-A1 ORGANIC/INORGANIC HYBRID NANOPARTICULATES MADE FROM IRON CARBOXYLATES SLC39A3, SLC40A1, AOC3 TSHR 2367/4885SMN1; SMN2 4491/4885CASP1 4082/4885
US-20100209354-A1 ORGANIC/INORGANIC HYBRID NANOPARTICULATES MADE FROM IRON CARBOXYLATES SLC39A3, SLC40A1, AOC3 TSHR 2404/4885SMN1; SMN2 4486/4885CASP1 4075/4885
US-11034711-B2 Low temperature process for the synthesis of MOF carboxylate nanoparticles FTO, TPI1, ACP1 TSHR 3308/4885SMN1; SMN2 4546/4885CASP1 3961/4885
US-11739112-B2 Low temperature process for the synthesis of MOF carboxylate nanoparticles FTO, TPI1, ACP1 TSHR 3308/4885SMN1; SMN2 4546/4885CASP1 3961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.