Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17A | Q9UEE5 | 9/20 | 0.48 |
| ▸ | SYK | P43405 | 6/20 | 0.45 |
| ▸ | ZAP70 | P43403 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | STK17B | O94768 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14983698 | 0.81 | GAA (0.50) | RXRAGRIN1GRIN2BP2RX3P2RX2 | |
| SCHEMBL25075278 | 0.76 | SYK (0.46) | STK17ASYKZAP70KCNH2AURKB | |
| SCHEMBL10517407 | 0.74 | KDM4E (0.40) | STK17ASYKRXRAGRIN1GRIN2B | |
| SCHEMBL31590759 | 0.74 | KDM4E (0.40) | STK17ASYKRXRAGRIN1GRIN2B | |
| Hydrochloric Acid SCHEMBL27685771 | 0.72 | ALDH1A1 (0.39) | RXRAGRIN1GRIN2B | |
| SCHEMBL18679035 | 0.72 | CXCR4 (0.41) | STK17ASYKZAP70KCNH2AURKB | |
| SCHEMBL14983677 | 0.71 | RAB9A (0.42) | RXRAGRIN1GRIN2B | |
| SCHEMBL12638743 | 0.71 | SORT1 (0.36) | SYKRXRAGRIN1GRIN2B | |
| SCHEMBL17563730 | 0.71 | CXCR4 (0.46) | STK17ASYKZAP70KCNH2AURKB | |
| SCHEMBL13034199 | 0.70 | CXCR4 (0.54) | SYKZAP70CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104428293-B | Adjust the benzimidazole of TNF α | UCB生物制药私人有限公司 | 2018-06-08 | — | — | CN | disclosed |
| WO-2013078254-A1 | BICYCLIC HETEROARYL DERIVATIVES AS KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2013-05-30 | — | — | WO | disclosed |