Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | MMP10 | P09238 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8201848 | 0.83 | RAB9A (0.43) | RAB9ANPSR1KDM4EKLK7KMT2A | |
| SCHEMBL14983698 | 0.75 | GAA (0.50) | KDM4EKMT2AALDH1A1RXRAGRIN1 | |
| SCHEMBL12316235 | 0.72 | THRA (0.34) | RAB9AKDM4EKLK7KMT2ACA12 | |
| SCHEMBL12412659 | 0.71 | SMN1; SMN2 (0.43) | ALDH1A1PLAUEGLN1HDAC3HDAC1 | |
| SCHEMBL12503461 | 0.71 | EGLN1 (0.40) | RAB9ANPSR1KDM4EKLK7CA12 | |
| SCHEMBL14983704 | 0.71 | STK17A (0.48) | RXRAGRIN1GRIN2B | |
| SCHEMBL23320696 | 0.71 | RAB9A (0.41) | RAB9AKDM4ECA12CA1CA2 | |
| SCHEMBL10707679 | 0.71 | AGBL2 (0.43) | RAB9ASORT1KMT2AALDH1A1MEN1 | |
| SCHEMBL21963629 | 0.71 | KMT2A (0.68) | RAB9AKDM4EKLK7KMT2ACA12 | |
| SCHEMBL12338165 | 0.70 | KDM4E (0.34) | RAB9ANPSR1KDM4EKLK7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013078254-A1 | BICYCLIC HETEROARYL DERIVATIVES AS KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2013-05-30 | — | — | WO | disclosed |