Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.90 |
| ▸ | MAPT | P10636 | 2/20 | 0.90 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.90 |
| ▸ | HTT | P42858 | 2/20 | 0.90 |
| ▸ | RAB9A | P51151 | 2/20 | 0.90 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.90 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.90 |
| ▸ | POLB | P06746 | 1/20 | 0.90 |
| ▸ | INSR | P06213 | 17/20 | 0.84 |
| ▸ | APP | P05067 | 1/20 | 0.73 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14984211 | 0.92 | INSR (1.00) | NSD2MAPTMAPK1HTTRAB9A | |
| Iodide SCHEMBL8387880 | 0.90 | INSR (0.97) | NSD2MAPTMAPK1HTTRAB9A | |
| Iodide SCHEMBL8387879 | 0.90 | INSR (0.97) | NSD2MAPTMAPK1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL8386848 | 0.90 | INSR (0.97) | NSD2MAPTMAPK1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL8386851 | 0.90 | INSR (0.97) | NSD2MAPTMAPK1HTTRAB9A | |
| SCHEMBL2442132 | 0.84 | APP (1.00) | NSD2MAPTMAPK1HTTRAB9A | |
| SCHEMBL2442135 | 0.84 | APP (1.00) | NSD2MAPTMAPK1HTTRAB9A | |
| SCHEMBL29409742 | 0.83 | APP (0.98) | NSD2MAPTMAPK1HTTRAB9A | |
| SCHEMBL17026625 | 0.83 | APP (0.98) | NSD2MAPTMAPK1HTTRAB9A | |
| SCHEMBL17026626 | 0.83 | APP (0.98) | NSD2MAPTMAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170056378-A1 | METHOD OF INHIBITING CANCER CELL, METHOD FOR DETECTING CANCER CELL, AND SYSTEM FOR DETECTING CANCER CELL | CANON KK (JP) | 2017-03-02 | — | — | US | disclosed |
| US-20160280921-A1 | DYES FOR ANALYSIS OF PROTEIN AGGREGATION | ENZO LIFE SCIENCES, INC. (US) | 2016-09-29 | — | — | US | disclosed |
| US-20150274715-A1 | CANCER CELL INHIBITORY DRUG AND CANCER STEM-CELL DETECTION PROBE | CANON KABUSHIKI KAISHA (JP) | 2015-10-01 | — | — | US | disclosed |
| US-20130137112-A1 | DYES FOR ANALYSIS OF PROTEIN AGGREGATION | ENZO LIFE SCIENCES, INC. | 2013-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137112-A1 | DYES FOR ANALYSIS OF PROTEIN AGGREGATION | CRYAA, CRYAB, HSPH1 | NSD2 4349/4885MAPT 17/4885MAPK1 2936/4885 |
| US-20170056378-A1 | METHOD OF INHIBITING CANCER CELL, METHOD FOR DETECTING CANCER CELL, AND SYSTEM FOR DETECTING CANCER CELL | MKI67, MCL1, ABCB1 | NSD2 3706/4885MAPT 4669/4885MAPK1 1037/4885 |
| US-20150274715-A1 | CANCER CELL INHIBITORY DRUG AND CANCER STEM-CELL DETECTION PROBE | MKI67, CD44, ABCB1 | NSD2 3373/4885MAPT 4340/4885MAPK1 602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.