Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 19/20 | 0.58 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14984199 | 0.86 | INSR (0.65) | INSRNSD2POLBMAPTMAPK1 | |
| SCHEMBL14984268 | 0.77 | INSR (0.82) | INSRNSD2POLBMAPTMAPK1 | |
| Iodide SCHEMBL8387888 | 0.73 | INSR (0.97) | INSRNSD2POLBMAPTMAPK1 | |
| Iodide SCHEMBL8387885 | 0.73 | INSR (0.97) | INSRNSD2POLBMAPTMAPK1 | |
| Iodide SCHEMBL34471322 | 0.72 | INSR (0.80) | INSRNSD2POLBMAPTMAPK1 | |
| SCHEMBL34467576 | 0.71 | INSR (1.00) | INSRNSD2POLBMAPTMAPK1 | |
| SCHEMBL14984211 | 0.71 | INSR (1.00) | INSRNSD2POLBMAPTMAPK1 | |
| Iodide SCHEMBL8390912 | 0.71 | INSR (0.98) | INSRNSD2POLBMAPTMAPK1 | |
| Iodide SCHEMBL8390913 | 0.71 | INSR (0.98) | INSRNSD2POLBMAPTMAPK1 | |
| Iodide SCHEMBL8387880 | 0.70 | INSR (0.97) | INSRNSD2POLBMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160280921-A1 | DYES FOR ANALYSIS OF PROTEIN AGGREGATION | ENZO LIFE SCIENCES, INC. (US) | 2016-09-29 | — | — | US | disclosed |
| US-20130137112-A1 | DYES FOR ANALYSIS OF PROTEIN AGGREGATION | ENZO LIFE SCIENCES, INC. | 2013-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137112-A1 | DYES FOR ANALYSIS OF PROTEIN AGGREGATION | CRYAA, CRYAB, HSPH1 | INSR 4485/4885NSD2 4349/4885POLB 1788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.