2-Picolinic Acid

2-Picolinic Acid

SCHEMBL149849

O=C(O)c1ccccn1.[Nd]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.95
L3MBTL1 Q9Y468 2/20 0.95
NAPRT Q6XQN6 1/20 0.95
P4HTM Q9NXG6 1/20 0.95
CES2 O00748 1/20 0.67
CES1 P23141 1/20 0.67
KMT2A Q03164 2/20 0.63
ALDH1A1 P00352 2/20 0.61
GSK3B P49841 1/20 0.55
KDM4E B2RXH2 4/20 0.53
NPC1 O15118 3/20 0.53
RAB9A P51151 3/20 0.53
MAPT P10636 2/20 0.53
PKM P14618 2/20 0.53
TDP1 Q9NUW8 2/20 0.52
ALOX15 P16050 1/20 0.52
TSHR P16473 1/20 0.52
ACMSD Q8TDX5 1/20 0.52
PTGS2 P35354 1/20 0.50
CTNNB1 P35222 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Picolinic Acid SCHEMBL29368665 0.98
2-Picolinic Acid SCHEMBL674837 0.98 LMNA (1.00) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL28737810 0.98 LMNA (1.00) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL36055 0.98
2-Picolinic Acid SCHEMBL7457912 0.98 LMNA (1.00) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL5667302 0.95 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL1469 0.95 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL20721125 0.95 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL22835776 0.95 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL1462616 0.95 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 426 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114497399-A Composite material, light-emitting diode and preparation method of light-emitting diode TCL科技集团股份有限公司 2022-05-13 CN claimed
CN-105646754-B Method for producing polydiene 株式会社普利司通 2018-08-07 CN claimed
US-9796800-B2 Process for producing polydienes BRIDGESTONE CORPORATION (JP) 2017-10-24 US claimed
CN-105646754-A Method of producing polydiene 株式会社普利司通 2016-06-08 CN claimed
US-20160108153-A1 PROCESS FOR PRODUCING POLYDIENES BRIDGESTONE CORPORATION (JP) 2016-04-21 US claimed
EP-3917976-B1 METHOD FOR PRODUCING POLYDIENES WITH REDUCED COLD FLOW BRIDGESTONE AMERICAS TIRE OPERATIONS LLC (US) 2026-04-15 EP disclosed
EP-3969490-B1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND TIRE COMPONENTS BRIDGESTONE CORP (JP) 2026-03-25 EP disclosed
US-20260035494-A1 METHOD FOR COLD FLOW REDUCTION OF ELASTOMERS GOODYEAR TIRE & RUBBER (US) 2026-02-05 US disclosed
US-20260002005-A1 DISULFUR DICHLORIDE AND ALKENYL ETHERS ADDITIVES FOR MOONEY JUMP GOODYEAR TIRE & RUBBER (US) 2026-01-01 US disclosed
US-20260001974-A1 DISULFUR DICHLORIDE AND SILANE/SILOXANE ADDITIVE FOR MOONEY JUMP GOODYEAR TIRE & RUBBER (US) 2026-01-01 US disclosed
US-20250389555-A1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-12-25 US disclosed
US-12410263-B2 Modified high-Cis polybutadiene polymer, related methods and rubber compositions BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-09-09 US disclosed
US-20050038215-A1 Lanthanide-based catalyst composition for producing cis-1,4-polydienes BRIDGESTONE CORPORATION (JP) 2005-02-17 US disclosed
US-20040116638-A1 Continuous process for the production of conjugated diene polymers having narrow molecular weight distribution and products therefrom BRIDGESTONE CORPORATION (JP) 2004-06-17 US disclosed
CN-1494556-A Continuous process for production of conjugated diene polymers having narrow molecular weight distribution and products therefrom ������������ʽ���� 2004-05-05 CN disclosed
US-6699813-B2 COMPOSITION THAT IS COMBINATION OF OR REACTION PRODUCT OF LANTHANIDE COMPOUND, ALKYLATING AGENT, NICKEL-CONTAINING COMPOUND, AND OPTIONALLY HALOGEN-CONTAINING COMPOUND THAT INCLUDES ONE OR MORE LABILE HALOGEN ATOMS BRIDGESTONE CORPORATION (JP) 2004-03-02 US disclosed
EP-1370593-A1 CONTINUOUS PROCESS FOR THE PRODUCTION OF CONJUGATED DIENE POLYMERS HAVING NARROW MOLECULAR WEIGHT DISTRIBUTION AND PRODUCTS THEREFROM Bridgestone Corporation (JP) 2003-12-17 EP disclosed
US-20030176276-A1 Lanthanide-based catalyst composition for the manufacture of polydienes BRIDGESTONE CORPORATION (JP) 2003-09-18 US disclosed
WO-2002068484-A1 CONTINUOUS PROCESS FOR THE PRODUCTION OF CONJUGATED DIENE POLYMERS HAVING NARROW MOLECULAR WEIGHT DISTRIBUTION AND PRODUCTS THEREFROM BRIDGESTONE CORPORATION (JP) 2002-09-06 WO disclosed
US-6437205-B1 USING NEODYMIUM CARBOXYLATE, ALUMINOXANE, AND TRIALKYL ALUMINUM CATALYST SYSTEM; GOOD WET TRACTION AND ROLLING RESISTANCE; GOOD PHYSICAL PROPERTIES BRIDGESTONE CORPORATION (JP) 2002-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035494-A1 METHOD FOR COLD FLOW REDUCTION OF ELASTOMERS ITGA1, HSPA1A, SHC1 LMNA 2148/4885L3MBTL1 709/4885NAPRT 4217/4885
US-20260001974-A1 DISULFUR DICHLORIDE AND SILANE/SILOXANE ADDITIVE FOR MOONEY JUMP DCLRE1A, DDR1, FDFT1 LMNA 3532/4885L3MBTL1 1317/4885NAPRT 4621/4885
US-20260002005-A1 DISULFUR DICHLORIDE AND ALKENYL ETHERS ADDITIVES FOR MOONEY JUMP MRE11, DDR1, DDB1 LMNA 3788/4885L3MBTL1 613/4885NAPRT 4619/4885
US-20250389555-A1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS MALT1, INO80C, RTCB LMNA 450/4885L3MBTL1 212/4885NAPRT 4654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.