Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 6/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1282816 | 0.81 | CTSD (0.46) | CTSDFDPSF2ADRA2BKCNH2 | |
| SCHEMBL23336901 | 0.80 | — | — | |
| SCHEMBL16596248 | 0.76 | CTSD (0.46) | CTSDFDPSF2ADRA2BKCNH2 | |
| SCHEMBL5495415 | 0.76 | CTSD (0.46) | CTSDFDPSF2ADRA2BKCNH2 | |
| SCHEMBL7054279 | 0.76 | LIMK1 (0.51) | CTSDFDPSF2ADRA2BKCNH2 | |
| SCHEMBL714498 | 0.76 | CTSD (0.46) | CTSDFDPSF2ADRA2BKCNH2 | |
| SCHEMBL1678422 | 0.76 | ADRA2B (0.49) | CTSDFDPSF2ADRA2BKCNH2 | |
| SCHEMBL3223115 | 0.76 | CTSD (0.46) | CTSDFDPSF2ADRA2BKCNH2 | |
| SCHEMBL6032869 | 0.76 | CYP2C19 (0.50) | CTSDF2RAD52ALDH1A1KDM4E | |
| SCHEMBL13552314 | 0.75 | ALDH1A1 (0.64) | CTSDMAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3153023-A1 | BENZOXAZOLE KINASE INHIBITORS AND METHODS OF USE | Intellikine, LLC (US) | 2017-04-12 | — | — | EP | disclosed |
| EP-2705181-B1 | COMBINATION PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | INTELLIKINE LLC (US) | 2016-12-21 | — | — | EP | disclosed |
| WO-2014151147-A1 | COMBINATION OF KINASE INHIBITORS AND USES THEREOF | INTELLIKINE, LLC (US) | 2014-09-25 | — | — | WO | disclosed |
| WO-2013078440-A2 | ENHANCED TREATMENT REGIMENS USING MTOR INHIBITORS | INTELLIKINE, LLC (US) | 2013-05-30 | — | — | WO | disclosed |