Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | PRKCI | P41743 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | DNM2 | P50570 | 2/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18290331 | 0.80 | ADRA2B (0.40) | CYP2C19BCHEHRH3RAD52PRKCI | |
| SCHEMBL171395 | 0.78 | ALDH1A1 (0.56) | CYP2C19ALDH1A1NCF1NOS1NOS2 | |
| SCHEMBL12468898 | 0.77 | CYP2C19 (0.45) | CYP2C19HRH3KDM4ENCF1GAA | |
| SCHEMBL3210499 | 0.77 | CHRNA7 (0.51) | CYP2C19HRH3GAA | |
| SCHEMBL10798745 | 0.77 | TAAR1 (0.52) | CYP2C19NOS2 | |
| SCHEMBL81430 | 0.77 | MAPT (0.67) | CYP2C19HRH3KDM4EALDH1A1POLB | |
| SCHEMBL18066566 | 0.76 | HRH3 (0.47) | CYP2C19HRH3KDM4ENOS1NOS2 | |
| SCHEMBL3223115 | 0.76 | CTSD (0.46) | BCHEKDM4EALDH1A1RAD52F2 | |
| SCHEMBL14985489 | 0.76 | CTSD (0.46) | BCHEKDM4EALDH1A1RAD52F2 | |
| SCHEMBL7054279 | 0.76 | LIMK1 (0.51) | F2CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219191-A1 | 3-Pyridinium Methyl Cephem Compound | SHIONOGI & CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| US-20070219191-A1 | 3-Pyridinium Methyl Cephem Compound | SHIONOGI & CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| US-7049285-B2 | Biocompatible polymers including peptide spacer | BIOPOLYMED INC. (KR) | 2006-05-23 | — | — | US | disclosed |
| US-20030185798-A1 | Biocompatible polymers including peptide spacer | BIOPOLYMED INC. (KR) | 2003-10-02 | — | — | US | disclosed |
| WO-2003037915-A1 | BIOCOMPATIBLE POLYMERS INCLUDING PEPTIDE SPACER | BIOPOLYMED INC. (KR) | 2003-05-08 | — | — | WO | disclosed |
| US-4203988-A | ANTISECRETORY AGENTS | MERCK & CO., INC. (US) | 1980-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030185798-A1 | Biocompatible polymers including peptide spacer | EEA1, SLC7A1, CD47 | CYP2C19 3197/4885BCHE 3139/4885HRH3 915/4885 |
| US-20070219191-A1 | 3-Pyridinium Methyl Cephem Compound | ABL1, CRKL, MGMT | CYP2C19 358/4885BCHE 828/4885HRH3 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.