SCHEMBL30301261

SCHEMBL30301261

CCc1cc(CC(C)C)c(N)cc1N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.36
ALOX12 P18054 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
VDR P11473 1/20 0.36
ALDH1A1 P00352 3/20 0.36
POLB P06746 2/20 0.36
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CYP1A2 P05177 1/20 0.35
CASP7 P55210 1/20 0.35
HIF1A Q16665 1/20 0.35
HSD17B10 Q99714 1/20 0.35
GABRA1 P14867 2/20 0.34
GABRB2 P47870 2/20 0.34
MAPT P10636 1/20 0.34
PARP1 P09874 1/20 0.33
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
AR P10275 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL169822 1.00 ALOX15 (0.36) ALOX15ALOX12TAAR1VDRALDH1A1
SCHEMBL118865 0.83 ALDH1A1 (0.46) ALOX15TAAR1ALDH1A1POLBCYP1A2
SCHEMBL27889316 0.80 VDR (0.38) ALOX15VDRALDH1A1CYP1A2CASP7
SCHEMBL3943095 0.77 GABRA1 (0.43) ALOX15ALDH1A1POLBHSD17B10GABRA1
SCHEMBL560872 0.77 ALDH1A1 (0.34) ALOX15VDRALDH1A1POLBCYP1A2
SCHEMBL29779644 0.77 ALDH1A1 (0.34) ALOX15VDRALDH1A1POLBCYP1A2
SCHEMBL12848647 0.77 GABRA1 (0.33) ALOX15VDRALDH1A1POLBMAPK1
SCHEMBL11468902 0.76 AR (0.42) ALOX15ALOX12TAAR1ALDH1A1POLB
SCHEMBL832574 0.75 ALDH1A1 (0.43) ALOX15TAAR1ALDH1A1POLBCYP1A2
SCHEMBL29779647 0.74 ALDH1A1 (0.35) ALOX15ALOX12TAAR1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4402191-A1 ONE-POT PROCESS FOR THE PRODUCTION OF POLYCARBODIIMIDE CURED POLYMERS BASF SE (DE) 2024-07-24 EP disclosed
WO-2023041443-A1 ONE-POT PROCESS FOR THE PRODUCTION OF POLYCARBODIIMIDE CURED POLYMERS BASF SE (DE) 2023-03-23 WO disclosed