Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2774777 | 0.70 | CYP2C9 (0.37) | NPC1RAB9ASMN1; SMN2PYGL | |
| SCHEMBL2964693 | 0.65 | DAPK3 (0.41) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11428615 | 0.65 | ALOX12 (0.54) | NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL11414717 | 0.65 | ALOX12 (0.54) | NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL11421493 | 0.63 | ALOX12 (0.51) | NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL14518218 | 0.60 | CYP2C9 (0.36) | — | |
| SCHEMBL10816029 | 0.60 | ALDH1A1 (0.51) | — | |
| SCHEMBL4493246 | 0.60 | ALDH1A1 (0.39) | RAB9A | |
| SCHEMBL11416104 | 0.59 | MAPT (0.45) | NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL31318182 | 0.58 | NOS3 (0.34) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011506452-A | — | — | 2011-03-03 | — | — | JP | claimed |
| EP-2240559-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | Chemtura Corporation (US) | 2010-10-20 | — | — | EP | claimed |
| WO-2009076090-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | CHEMTURA CORPORATION (US) | 2009-06-18 | — | — | WO | claimed |
| EP-2240559-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | Chemtura Corporation (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009076090-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | CHEMTURA CORPORATION (US) | 2009-06-18 | — | — | WO | disclosed |