SCHEMBL14988922

SCHEMBL14988922

Cc1cccc(NS(=O)(=O)c2cc[c]cc2)n1

nearest known ligand 0.74

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.74
KDM4E B2RXH2 5/20 0.74
HPGD P15428 5/20 0.74
HSD17B10 Q99714 3/20 0.74
L3MBTL1 Q9Y468 1/20 0.68
HSD11B1 P28845 8/20 0.67
LMNA P02545 3/20 0.62
GLA P06280 1/20 0.55
HTT P42858 1/20 0.53
MAPT P10636 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29967633 0.85 KDM4E (1.00) ALDH1A1KDM4EHPGDHSD17B10L3MBTL1
SCHEMBL6026817 0.85 KDM4E (1.00) ALDH1A1KDM4EHPGDHSD17B10L3MBTL1
SCHEMBL3486583 0.84 HSD11B1 (0.91) ALDH1A1KDM4EHPGDHSD17B10L3MBTL1
SCHEMBL29506329 0.84 HSD11B1 (0.91) ALDH1A1KDM4EHPGDHSD17B10L3MBTL1
SCHEMBL10031608 0.81 ALDH1A1 (0.74) ALDH1A1KDM4EHPGDHSD17B10L3MBTL1
SCHEMBL6027289 0.81 ALDH1A1 (0.74) ALDH1A1KDM4EHPGDHSD17B10L3MBTL1
SCHEMBL25735979 0.81 HSD11B1 (0.91) ALDH1A1KDM4EHPGDHSD17B10L3MBTL1
SCHEMBL6027723 0.79 ALDH1A1 (0.70) ALDH1A1KDM4EHPGDHSD17B10L3MBTL1
SCHEMBL3925744 0.78 LMNA (0.78) ALDH1A1KDM4EHPGDHSD17B10L3MBTL1
SCHEMBL12640446 0.77 HSD11B1 (1.00) HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2599480-A1 Compounds for the treatment of influenza Universität Innsbruck (AT) 2013-06-05 EP claimed
EP-2599480-A1 Compounds for the treatment of influenza Universität Innsbruck (AT) 2013-06-05 EP disclosed