SCHEMBL29967633

SCHEMBL29967633

Cc1cccc(NS(=O)(=O)c2ccccc2)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 1.00
ALDH1A1 P00352 5/20 1.00
HPGD P15428 5/20 1.00
HSD17B10 Q99714 3/20 1.00
HSD11B1 P28845 8/20 0.82
LMNA P02545 3/20 0.76
L3MBTL1 Q9Y468 1/20 0.74
GLA P06280 1/20 0.59
TSHR P16473 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
AGTR1 P30556 1/20 0.57
GLO1 Q04760 1/20 0.57
PAX8 Q06710 1/20 0.57
SLC40A1 Q9NP59 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6026817 1.00 KDM4E (1.00) KDM4EALDH1A1HPGDHSD17B10HSD11B1
SCHEMBL29506329 0.88 HSD11B1 (0.91) KDM4EALDH1A1HPGDHSD17B10HSD11B1
SCHEMBL3486583 0.88 HSD11B1 (0.91) KDM4EALDH1A1HPGDHSD17B10HSD11B1
SCHEMBL25735979 0.85 HSD11B1 (0.91) KDM4EALDH1A1HPGDHSD17B10HSD11B1
SCHEMBL10031608 0.85 ALDH1A1 (0.74) KDM4EALDH1A1HPGDHSD17B10HSD11B1
SCHEMBL6027289 0.85 ALDH1A1 (0.74) KDM4EALDH1A1HPGDHSD17B10HSD11B1
SCHEMBL14988922 0.85 ALDH1A1 (0.74) KDM4EALDH1A1HPGDHSD17B10HSD11B1
SCHEMBL9927453 0.83 HSD11B1 (1.00) KDM4EALDH1A1HPGDHSD17B10HSD11B1
SCHEMBL6027723 0.83 ALDH1A1 (0.70) KDM4EALDH1A1HPGDHSD17B10HSD11B1
SCHEMBL3925744 0.82 LMNA (0.78) KDM4EALDH1A1HPGDHSD17B10HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026107076-A1 CDK2 INHIBITOR COMPOUNDS ALEKSIA THERAPEUTICS, INC. (US) 2026-05-21 WO disclosed
CN-115124459-A Method for selectively nitrating N- (2-pyridyl) benzene sulfonamide compound 宁波大学 2022-09-30 CN disclosed