SCHEMBL328926

SCHEMBL328926

C=C(C)C(=O)OC(O)(O)Cn1c(=O)[nH]c(=O)[nH]c1=O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15152 0.86 TSHR (0.33) TSHR
SCHEMBL16227843 0.85 TSHR (0.32) TSHR
SCHEMBL1823228 0.85
SCHEMBL149919 0.78 THRB (0.37) TSHR
Methacrylic Acid SCHEMBL904578 0.76 APEX1 (0.33)
Methacrylic Acid SCHEMBL1008210 0.76 APEX1 (0.33)
SCHEMBL9696445 0.73 TSHR (0.32) TSHR
SCHEMBL831001 0.72 THRB (0.42) TSHR
SCHEMBL28718297 0.71 TSHR (0.36) TSHR
SCHEMBL7638251 0.71 TSHR (0.37) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3955881-B1 DENTAL COMPOSITION DENTSPLY SIRONA INC (US) 2024-04-24 EP disclosed
EP-3898772-B1 DENTAL COMPOSITION DENTSPLY DETREY GMBH (DE) 2024-03-13 EP disclosed
US-11844849-B2 Dental compositions comprising nanoparticles providing a refractive index differential between polymerizable resin and filler 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-12-19 US disclosed
WO-2023239790-A2 ENHANCING DENTIN BONDING DURABILITY USING QUATERNARY PYRIDINIUM SALTS ADA Science and Research Institute LLC (US) 2023-12-14 WO disclosed
EP-3529239-B1 PHOTOINITIATORS WITH PROTECTED CARBONYL GROUP 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-02-15 EP disclosed
US-11545614-B2 Ionic polymer compositions SABIC GLOBAL TECHNOLOGIES, B.V. (NL) 2023-01-03 US disclosed
US-20220202658-A1 DENTAL COMPOSITION DENTSPLY SIRONA INC. (US) 2022-06-30 US disclosed
US-11319392-B2 Compositions and methods to antibacterial nanogel and hydrolytically stable antibacterial nanogel for dental compositions DENTSPLY SIRONA INC. (US) 2022-05-03 US disclosed
US-20220125687-A1 DENTAL COMPOSITIONS COMPRISING NANOPARTICLES PROVIDING A REFRACTIVE INDEX DIFFERENTIAL BETWEEN POLYMERIZABLE RESIN AND FILLER SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2022-04-28 US disclosed
EP-3955881-A2 DENTAL COMPOSITION Dentsply Sirona Inc. (US) 2022-02-23 EP disclosed
US-20020028302-A1 Crosslinkable resin compositions TOAGOSEI CO. LTD. 2002-03-07 US disclosed
EP-1167395-A1 Crosslinkable resin compositions Toagosei Co., Ltd. (JP) 2002-01-02 EP disclosed
US-6331080-B1 Optical fiber connector using colored photocurable adhesive 3M INNOVATIVE PROPERTIES COMPANY 2001-12-18 US disclosed
EP-1135448-A1 OPTICAL FIBER CONNECTOR USING COLORED PHOTOCURABLE ADHESIVE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2001-09-26 EP disclosed
EP-1053495-A1 OPTICAL FIBER CONNECTOR USING PHOTOCURABLE ADHESIVE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-11-22 EP disclosed
US-6151433-A Optical fiber connector using photocurable adhesive 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-11-21 US disclosed
US-6085004-A Optical fiber connector using photocurable adhesive 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-07-04 US disclosed
WO-2000022060-A1 OPTICAL FIBER CONNECTOR USING COLORED PHOTOCURABLE ADHESIVE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-04-20 WO disclosed
WO-1999040465-A1 OPTICAL FIBER CONNECTOR USING PHOTOCURABLE ADHESIVE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-08-12 WO disclosed
US-4691045-A Hydroxyl group-containing (meth)acrylate oligomer, prepolymer therefrom, and method for use thereof NIPPON SHOKUBAI KAGAKU CO., LTD. (JP) 1987-09-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11319392-B2 Compositions and methods to antibacterial nanogel and hydrolytically stable antibacterial nanogel for dental compositions RAB5IF, CLPP, PGLS TSHR 4800/4885
US-20220202658-A1 DENTAL COMPOSITION CAD, PHOSPHO1, PLA2G2C TSHR 4730/4885
US-20220125687-A1 DENTAL COMPOSITIONS COMPRISING NANOPARTICLES PROVIDING A REFRACTIVE INDEX DIFFERENTIAL BETWEEN POLYMERIZABLE RESIN AND FILLER EPN1, ARCN1, RARA TSHR 3320/4885
US-11844849-B2 Dental compositions comprising nanoparticles providing a refractive index differential between polymerizable resin and filler EPN1, ARCN1, RARA TSHR 3320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.