SCHEMBL152169

SCHEMBL152169

C=CC(=O)OCCC(O)(CCOC(=O)C=C)Cn1c(=O)[nH]c(=O)[nH]c1=O

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.39
ALDH1A1 P00352 4/20 0.39
TP53 P04637 3/20 0.39
HIF1A Q16665 3/20 0.39
CYP3A4 P08684 2/20 0.39
HSD17B10 Q99714 1/20 0.39
HPGD P15428 1/20 0.36
THRB P10828 2/20 0.34
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1022968 0.80 TSHR (0.44) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL2488022 0.79
SCHEMBL149919 0.79 THRB (0.37) TSHRALDH1A1THRB
SCHEMBL3779899 0.78 APEX1 (0.31)
SCHEMBL7028000 0.78
SCHEMBL28004951 0.78 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL6906483 0.77 TSHR (0.39) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL21816726 0.77 TSHR (0.38) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL27704679 0.77 TSHR (0.53) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL152168 0.76 TSHR (0.41) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 490 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11072849-B2 Actinic-ray-curable coating material composition and layered product MITSUBISHI CHEMICAL CORPORATION (JP) 2021-07-27 US claimed
CN-108603048-B Active energy ray-curable composition and laminate 三菱化学株式会社 2020-06-16 CN claimed
US-20190003032-A1 ACTINIC-RAY-CURABLE COATING MATERIAL COMPOSITION AND LAYERED PRODUCT MITSUBISHI CHEMICAL CORPORATION (JP) 2019-01-03 US claimed
EP-1813972-B1 Alignment Film NIPPON KAYAKU KK (JP) 2012-10-10 EP claimed
US-7445820-B2 Optical films comprising a UV-curable alignment film and a liquid crystal compound NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2008-11-04 US claimed
US-6916540-B2 Second layer formed under the first layercomprising a needle-like antimony-containing tin oxide to reduce static JSR CORPORATION (JP) 2005-07-12 US claimed
EP-0716102-B1 TRANSPARENT PLASTIC MATERIAL, OPTICAL ARTICLE MADE THEREFROM, AND PRODUCTION PROCESS SEIKO EPSON CORP (JP) 2002-02-06 EP claimed
US-4526920-A Contains poly(meth)acrylic ester of oxy or polyoxyalkane polyol, polymerization initiator, filler MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1985-07-02 US claimed
CN-116075368-B Resin composition, cured product, method for producing same, and laminate 三菱化学株式会社 2024-06-11 CN disclosed
EP-3677649-B1 ACTIVE ENERGY RAY-CURABLE COATING COMPOSITION NIPPON PAINT AUTOMOTIVE COATINGS CO LTD (JP) 2024-04-24 EP disclosed
WO-2024058138-A1 HEAD-UP DISPLAY SYSTEM AND OPTICALLY FUNCTIONAL LAYER FOR HEAD-UP DISPLAY 日本化薬株式会社 2024-03-21 WO disclosed
CN-117730111-A Active energy ray-curable coating composition and molded article DIC株式会社 2024-03-19 CN disclosed
EP-3730308-B1 PLANOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF PRODUCING PLANOGRAPHIC PRINTING PLATE FUJIFILM CORP (JP) 2024-02-28 EP disclosed
EP-4310558-A1 OPTICAL FUNCTIONAL FILM FOR HEAD-UP DISPLAY, OPTICAL LAMINATE, FUNCTIONAL GLASS, AND HEAD-UP DISPLAY SYSTEM Nippon Kayaku Kabushiki Kaisha (JP) 2024-01-24 EP disclosed
EP-0243501-A1 CURABLE COMPOSITION AND METHOD FOR MOLDING IT SHOWA DENKO KABUSHIKI KAISHA (JP) 1987-11-04 EP disclosed
US-4686166-A HIGH IMAGE DENSITY, ANTIFOGGING AGENT HITACHI CHEMICAL CO. (JP) 1987-08-11 US disclosed
US-4664734-A RADIATION POLYMERIZATION FUJI PHOTO FILM CO., LTD. (JP) 1987-05-12 US disclosed
EP-0100688-B1 CURABLE COATING COMPOSITION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1987-04-22 EP disclosed
US-4526920-A Contains poly(meth)acrylic ester of oxy or polyoxyalkane polyol, polymerization initiator, filler MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1985-07-02 US disclosed
EP-0100688-A2 Curable coating composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1984-02-15 EP disclosed