SCHEMBL4411314

SCHEMBL4411314

Brc1cc2c3c(c1)CCc1cccc(c1-3)CC2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HSD17B3 P37058 5/20 0.35
SLC6A2 P23975 1/20 0.34
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
SLC6A4 P31645 1/20 0.34
PNMT P11086 1/20 0.33
SRD5A1 P18405 1/20 0.33
SRD5A2 P31213 1/20 0.33
ASIC3 Q9UHC3 1/20 0.33
ALDH1A1 P00352 2/20 0.32
MAPK1 P28482 1/20 0.32
TSHR P16473 1/20 0.32
HPGD P15428 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1004636 0.91 SLC6A2 (0.38) TDP1L3MBTL1HSD17B3SLC6A2HTR2A
SCHEMBL1569413 0.87 PNMT (0.34) TDP1L3MBTL1PNMTSRD5A1SRD5A2
SCHEMBL29388679 0.81 TSHR (0.44) TDP1L3MBTL1HTR2AHTR2CSRD5A1
SCHEMBL149965 0.81 TSHR (0.44) TDP1L3MBTL1HTR2AHTR2CSRD5A1
SCHEMBL979162 0.79 CYP19A1 (0.32) PNMTSRD5A1SRD5A2ASIC3
SCHEMBL25118730 0.78 ALDH1A1 (0.44) TDP1L3MBTL1HSD17B3SLC6A2SLC6A4
SCHEMBL1698292 0.75 PTGS2 (0.38) TDP1SRD5A1SRD5A2TSHRHPGD
SCHEMBL5571743 0.75 MAPT (0.40) TDP1HSD17B3ALDH1A1TSHRHPGD
SCHEMBL28121136 0.74 TSHR (0.35) TDP1L3MBTL1PNMTALDH1A1TSHR
SCHEMBL5390002 0.73 NPSR1 (0.41) TDP1L3MBTL1HSD17B3SLC6A2HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230095563-A1 ORGANIC COMPOUND, ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY APPARATUS, PHOTOELECTRIC CONVERSION APPARATUS, ELECTRONIC APPARATUS, ILLUMINATION APPARATUS, MOVING OBJECT, AND EXPOSURE LIGHT SOURCE CANON KABUSHIKI KAISHA (JP) 2023-03-30 US disclosed
CN-111170874-B Arylamine compound and organic electroluminescent device thereof 长春海谱润斯科技股份有限公司 2021-02-26 CN disclosed
CN-111170874-A Arylamine compound and organic electroluminescent device thereof 长春海谱润斯科技有限公司 2020-05-19 CN disclosed
US-20090321729-A1 Anthracene Derivatives and Organic Electroluminescent Devices Made by Using the Same IDEMITSU KOSAN CO., LTD. (JP) 2009-12-31 US disclosed
US-20050233165-A1 Anthracene derivatives and organic electroluminescent devices made by using the same IDEMITSU KOSAN CO., LTD. (JP) 2005-10-20 US disclosed
EP-1533289-A1 ANTHRACENE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICES MADE BY USING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2005-05-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230095563-A1 ORGANIC COMPOUND, ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY APPARATUS, PHOTOELECTRIC CONVERSION APPARATUS, ELECTRONIC APPARATUS, ILLUMINATION APPARATUS, MOVING OBJECT, AND EXPOSURE LIGHT SOURCE L1CAM, ORMDL3, TLL1 TDP1 4438/4885L3MBTL1 279/4885HSD17B3 3718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.