SCHEMBL982854

SCHEMBL982854

c1cc2c3c(c1)Cc1cccc(c1-3)CC2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
CYP3A4 P08684 2/20 0.46
MEN1 O00255 2/20 0.46
ALDH1A1 P00352 2/20 0.46
MAPT P10636 2/20 0.46
KMT2A Q03164 2/20 0.46
USP2 O75604 1/20 0.46
HPN P05981 1/20 0.46
ALOX5 P09917 1/20 0.46
THRB P10828 1/20 0.46
ALOX15 P16050 1/20 0.46
PTGS1 P23219 1/20 0.46
PDE4A P27815 1/20 0.46
KDR P35968 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
SIRT5 Q9NXA8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
HRH3 Q9Y5N1 1/20 0.46
DRD2 P14416 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL149965 0.90 TSHR (0.44) TSHRCYP3A4MEN1ALDH1A1MAPT
SCHEMBL29388679 0.90 TSHR (0.44) TSHRCYP3A4MEN1ALDH1A1MAPT
SCHEMBL5399227 0.90 TSHR (0.52) TSHRCYP3A4MEN1ALDH1A1MAPT
SCHEMBL1004636 0.82 SLC6A2 (0.38) TSHRCYP3A4MEN1ALDH1A1MAPT
SCHEMBL19398254 0.75 CYP3A4 (0.41) TSHRCYP3A4MEN1ALDH1A1MAPT
SCHEMBL250734 0.73 CYP2A6 (0.65) TSHRALOX15HSD17B10DRD2CYP2A6
SCHEMBL5571743 0.73 MAPT (0.40) TSHRCYP3A4MEN1ALDH1A1MAPT
SCHEMBL4411314 0.73 TDP1 (0.38) TSHRMEN1ALDH1A1MAPTKMT2A
SCHEMBL10596221 0.71 ALDH1A1 (0.43) TSHRCYP3A4MEN1ALDH1A1MAPT
SCHEMBL19113839 0.71 TSHR (0.43) TSHRCYP3A4MEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022100704-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT APPARATUS AND DISPLAY DEVICE 阜阳欣奕华材料科技有限公司 2022-05-19 WO disclosed
US-9567287-B2 Compound for organic light-emitting diode and organic light-emitting diode including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-14 US disclosed
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed
US-20140209872-A1 COMPOUND, ORGANIC LIGHT EMITTING DEVICE INCLUDING THE COMPOUND, AND FLAT DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-31 US disclosed
US-20130328021-A1 COMPOUND FOR ORGANIC LIGHT-EMITTING DEVICE AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2013-12-12 US disclosed
US-20130270524-A1 COMPOUND FOR ORGANIC LIGHT-EMITTING DIODE AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2013-10-17 US disclosed
US-8329953-B2 Cyclopentaphenanthrene-based compound and organic electroluminescent device using the same SAMSUNG DISPLAY CO., LTD. (KR) 2012-12-11 US disclosed
US-7990053-B2 Cyclopentaphenanthrene-based compound and organic electroluminescent device using the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-08-02 US disclosed
US-7919654-B2 Cyclopentaphenanthrene-based compound and organic electroluminescent device using the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-04-05 US disclosed
US-7875367-B2 cyclopentaphenanthrene-based compound which is adapted for both dry and wet processes, and has excellent thermal stability and good charge transport and emission characteristics SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-01-25 US disclosed
US-7854999-B2 Organoelectroluminescent compound and organoelectroluminescent device employing the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-12-21 US disclosed
US-20100298607-A1 CYCLOPENTAPHENANTHRENE-BASED COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-11-25 US disclosed
US-20100289018-A1 CYCLOPENTAPHENANTHRENE-BASED COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-11-18 US disclosed
US-7833635-B2 Organoelectroluminescent compound and organoelectroluminescent device employing the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-11-16 US disclosed
US-7781579-B2 Cyclopentaphenanthrene-based compound and organic electroluminescent device using the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-08-24 US disclosed
US-20090092853-A1 Cyclopentaphenanthrene-based compound and organic light emitting device employing the same SAMSUNG DISPLAY CO., LTD. (KR) 2009-04-09 US disclosed
US-20080100207-A1 Organoelectroluminescent compound and organoelectroluminescent device employing the same SAMSUNG DISPLAY CO., LTD. (KR) 2008-05-01 US disclosed
US-20080093987-A1 Organoelectroluminescent compound and organoelectroluminescent device employing the same SAMSUNG DISPLAY CO., LTD. (KR) 2008-04-24 US disclosed
US-20080079356-A1 Organoelectroluminescent compound and organoelectroluminescent device employing the same SAMSUNG DISPLAY CO., LTD. (KR) 2008-04-03 US disclosed
US-20070290610-A1 Cyclopentaphenanthrene-based compound and organic electroluminescent device using the same SAMSUNG DISPLAY CO., LTD. (KR) 2007-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090092853-A1 Cyclopentaphenanthrene-based compound and organic light emitting device employing the same ABCB1, ARNT, PPOX TSHR 4738/4885CYP3A4 34/4885MEN1 3855/4885
US-20080100207-A1 Organoelectroluminescent compound and organoelectroluminescent device employing the same PPOX, EML4, DDT TSHR 4775/4885CYP3A4 50/4885MEN1 2383/4885
US-20100298607-A1 CYCLOPENTAPHENANTHRENE-BASED COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME EML4, EED, LAGE3 TSHR 4879/4885CYP3A4 201/4885MEN1 3661/4885
US-20130270524-A1 COMPOUND FOR ORGANIC LIGHT-EMITTING DIODE AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME AOX1, ALDH1A2, CRY1 TSHR 3505/4885CYP3A4 31/4885MEN1 2554/4885
US-20130328021-A1 COMPOUND FOR ORGANIC LIGHT-EMITTING DEVICE AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, ALDH1A2, AOX1 TSHR 4362/4885CYP3A4 52/4885MEN1 842/4885
US-20070290610-A1 Cyclopentaphenanthrene-based compound and organic electroluminescent device using the same EML4, EED, LAGE3 TSHR 4879/4885CYP3A4 201/4885MEN1 3661/4885
US-20080093987-A1 Organoelectroluminescent compound and organoelectroluminescent device employing the same PPOX, EML4, ALPL TSHR 4765/4885CYP3A4 66/4885MEN1 2247/4885
US-20080079356-A1 Organoelectroluminescent compound and organoelectroluminescent device employing the same PPOX, EML4, ALPL TSHR 4774/4885CYP3A4 51/4885MEN1 2453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.