Known targets — ChEMBL curated mechanism
S1PR1S1PR2S1PR3S1PR4S1PR5rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Thiamine Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | TKT | P29401 | 10/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiamine Ion SCHEMBL6274357 | 1.00 | HSP90AA1 (0.67) | HSP90AA1TDP1TKTLMNAALDH1A1 | |
| Thiamine Ion SCHEMBL6274356 | 0.99 | HSP90AA1 (0.68) | HSP90AA1TDP1TKTLMNAALDH1A1 | |
| Thiamine Ion SCHEMBL29858574 | 0.99 | HSP90AA1 (0.68) | HSP90AA1TDP1TKTLMNAALDH1A1 | |
| Thiamine Ion SCHEMBL1499696 | 0.99 | HSP90AA1 (0.68) | HSP90AA1TDP1TKTLMNAALDH1A1 | |
| Thiamine Ion SCHEMBL7786248 | 0.97 | HSP90AA1 (0.66) | HSP90AA1TDP1TKTLMNAALDH1A1 | |
| Thiamine Ion SCHEMBL29908533 | 0.96 | HSP90AA1 (0.64) | HSP90AA1TDP1TKTLMNAALDH1A1 | |
| Thiamine Ion SCHEMBL28650146 | 0.92 | HSP90AA1 (0.68) | HSP90AA1TDP1TKTLMNAALDH1A1 | |
| Thiamine Ion SCHEMBL5329756 | 0.92 | HSP90AA1 (0.69) | HSP90AA1TDP1TKTLMNAALDH1A1 | |
| Thiamine Ion SCHEMBL6831590 | 0.92 | HSP90AA1 (0.69) | HSP90AA1TDP1TKTLMNAALDH1A1 | |
| Thiamine Ion SCHEMBL6274353 | 0.91 | HSP90AA1 (0.68) | HSP90AA1TDP1TKTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230071051-A1 | EDIBLE OIL/FAT COMPOSITION HAVING BACTERIOSTATIC EFFECT | J-OIL MILLS, INC. (JP) | 2023-03-09 | — | — | US | claimed |
| CN-114980749-A | Edible oil composition with antibacterial effect | J-制油株式会社 | 2022-08-30 | — | — | CN | claimed |
| WO-2021125324-A1 | EDIBLE OIL/FAT COMPOSITION HAVING BACTERIOSTATIC EFFECT | アサマ化成株式会社 | 2021-06-24 | — | — | WO | claimed |
| JP-7016087-A | — | — | None | — | — | JP | disclosed |
| JP-4311369-A | — | — | None | — | — | JP | disclosed |
| JP-4311369-A | — | — | None | — | — | JP | disclosed |
| JP-3067573-A | — | — | None | — | — | JP | disclosed |
| JP-7067548-A | — | — | None | — | — | JP | disclosed |
| JP-54113435-A | — | — | None | — | — | JP | disclosed |
| JP-61204107-A | — | — | None | — | — | JP | disclosed |
| JP-63126450-A | — | — | None | — | — | JP | disclosed |
| JP-H04311369-A | WATER-SOLUBLE SOLUTION COMPOSITION OF THIAMINE LAURYL SULFATE | MEIYUU SANGYO KK | 1992-11-04 | — | — | JP | disclosed |
| JP-H04311369-A | WATER-SOLUBLE SOLUTION COMPOSITION OF THIAMINE LAURYL SULFATE | MEIYUU SANGYO KK | 1992-11-04 | — | — | JP | disclosed |
| US-5064829-A | Mannitol | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-11-12 | — | — | US | disclosed |
| JP-H0367573-A | COMPOSITION FOR STERILIZATION | NAKANO VINEGAR CO LTD | 1991-03-22 | — | — | JP | disclosed |
| EP-0390435-A1 | Vitamin B group compound composition and its production | Takeda Chemical Industries, Ltd. (JP) | 1990-10-03 | — | — | EP | disclosed |
| JP-H01305007-A | COMPOSITION FOR STERILIZING FOOD AND DRINK AND COOKING TOOL | NAKANO VINEGAR CO LTD | 1989-12-08 | — | — | JP | disclosed |
| JP-S63126450-A | PRODUCTION OF DRIED GLAIR | Q P CORP | 1988-05-30 | — | — | JP | disclosed |
| JP-S61204107-A | METHOD FOR CULTIVATING BASIDIOMYCETE | TANABE SEIYAKU CO LTD | 1986-09-10 | — | — | JP | disclosed |
| JP-S54113435-A | PESTICIDE FOR CONTROLLING BLIGHTS OF FRUITS DURING STORAGE | NIPPON NOHYAKU CO LTD | 1979-09-05 | — | — | JP | disclosed |