Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Thiamine Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | TKT | P29401 | 10/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiamine Ion SCHEMBL6831590 | 1.00 | HSP90AA1 (0.69) | HSP90AA1TDP1TKTLMNAALDH1A1 | |
| Thiamine Ion SCHEMBL1499694 | 0.94 | HSP90AA1 (0.68) | HSP90AA1TDP1TKTLMNAALDH1A1 | |
| Thiamine Ion SCHEMBL6274353 | 0.94 | HSP90AA1 (0.68) | HSP90AA1TDP1TKTLMNAALDH1A1 | |
| Thiamine Ion SCHEMBL7786248 | 0.93 | HSP90AA1 (0.66) | HSP90AA1TDP1TKTLMNAALDH1A1 | |
| Thiamine Ion SCHEMBL1499696 | 0.92 | HSP90AA1 (0.68) | HSP90AA1TDP1TKTLMNAALDH1A1 | |
| Thiamine Ion SCHEMBL6274356 | 0.92 | HSP90AA1 (0.68) | HSP90AA1TDP1TKTLMNAALDH1A1 | |
| Thiamine Ion SCHEMBL28650146 | 0.92 | HSP90AA1 (0.68) | HSP90AA1TDP1TKTLMNAALDH1A1 | |
| Thiamine Ion SCHEMBL29858574 | 0.92 | HSP90AA1 (0.68) | HSP90AA1TDP1TKTLMNAALDH1A1 | |
| Thiamine Ion SCHEMBL7786252 | 0.92 | HSP90AA1 (0.68) | HSP90AA1TDP1TKTLMNAALDH1A1 | |
| Thiamine Ion SCHEMBL1499697 | 0.92 | HSP90AA1 (0.67) | HSP90AA1TDP1TKTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119384278-A | Method for treating mental diseases | 上海日馨医药科技股份有限公司 | 2025-01-28 | — | — | CN | claimed |
| WO-2023236781-A1 | METHOD FOR TREATING MENTAL DISEASES | 上海日馨医药科技股份有限公司 | 2023-12-14 | — | — | WO | claimed |
| CN-109651356-B | Method for preparing thiamine dilauryl sulfate | 江西天新药业股份有限公司 | 2020-03-10 | — | — | CN | claimed |
| CN-109864072-A | A kind of Hostathion composite insecticide | 徐州农丰生物化工有限公司 | 2019-06-11 | — | — | CN | claimed |
| CN-109651356-A | The method for preparing thiamine dilauryl sulfate | 江西天新药业股份有限公司 | 2019-04-19 | — | — | CN | claimed |
| CN-108849551-A | A kind of excrement cleaning method of raising shed | 张诗敏 | 2018-11-23 | — | — | CN | claimed |
| CN-108739861-A | A kind of pig house that pig growth activity can be improved air type disinfectant | 安徽翠平生态农业科技发展有限公司 | 2018-11-06 | — | — | CN | claimed |
| CN-108552268-A | A kind of sterile avirulent ginger disinfectant | 临泉县盈昌农副产品有限公司 | 2018-09-21 | — | — | CN | claimed |
| CN-108323339-A | A kind of Grafted Eggplant method | 舒城县汤池镇昌涛生态蔬菜种植专业合作社 | 2018-07-27 | — | — | CN | claimed |
| WO-2018124528-A1 | METHOD FOR PREPARING THIAMINE DILAURYL SULFATE WITHOUT USING ORGANIC SOLVENT | CHOI TAE HO (KR) | 2018-07-05 | — | — | WO | claimed |
| CN-105010333-B | Bactericide and its application | 中国农业科学院蔬菜花卉研究所 | 2017-12-08 | — | — | CN | claimed |
| CN-107318889-A | A kind of disinfectant for vegetables | 徐州农丰生物化工有限公司 | 2017-11-07 | — | — | CN | claimed |
| US-20170312293-A1 | ANTIMICROBIAL WATER DISPERSIBLE COMPOSITION COMPRISING ZINC PYRITHIONE | KOLON LIFE SCIENCE, INC. (KR) | 2017-11-02 | — | — | US | claimed |
| EP-3219208-A1 | ANTIMICROBIAL WATER DISPERSIBLE COMPOSITION COMPRISING ZINC PYRITHIONE | Kolon Life Science (KR) | 2017-09-20 | — | — | EP | claimed |
| CN-106998691-A | Antibacterial aqueous dispersion composition containing zinc pyrithione | 可隆生命科学株式会社 | 2017-08-01 | — | — | CN | claimed |
| CN-106508961-A | Disinfectant | 威海裕隆水产开发有限公司 | 2017-03-22 | — | — | CN | claimed |
| CN-105010333-A | Bactericide and use thereof | INST VEGETABLES & FLOWERS CAAS | 2015-11-04 | — | — | CN | claimed |
| CN-103732068-A | Pesticide containing aqueous thiamine dilauryl sulfate for controlling and preventing plant diseases | DOOSANECOBIZNET CO LTD | 2014-04-16 | — | — | CN | claimed |
| CN-1091359-C | Instant food with balanced nutrients | WANG YONGHONG (CN) | 2002-09-25 | — | — | CN | claimed |
| CN-1270771-A | Instant food with balanced nutrients | WANG YONGHONG (CN) | 2000-10-25 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170312293-A1 | ANTIMICROBIAL WATER DISPERSIBLE COMPOSITION COMPRISING ZINC PYRITHIONE | WARS1, TST, SLC19A2 | HSP90AA1 1779/4885TDP1 577/4885TKT 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.