Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.31 |
| ▸ | CTSG | P08311 | 2/20 | 0.31 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.31 |
| ▸ | CMA1 | P23946 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14997679 | 0.87 | FFAR1 (0.35) | MEN1KMT2ABLMPRSS1CTSG | |
| SCHEMBL23005253 | 0.72 | KMT2A (0.34) | MEN1ALDH1A1KMT2ASIGMAR1POLB | |
| SCHEMBL18029421 | 0.70 | MEN1 (0.35) | MEN1KMT2ABLMPRSS1CTSG | |
| SCHEMBL21810875 | 0.70 | KMT2A (0.35) | KMT2A | |
| SCHEMBL9607156 | 0.69 | CTSK (0.31) | CTSK | |
| SCHEMBL14998074 | 0.69 | FFAR1 (0.33) | MEN1ALDH1A1KMT2ASIGMAR1PRSS1 | |
| SCHEMBL28896083 | 0.68 | SIGMAR1 (0.45) | MEN1ALDH1A1KMT2ASIGMAR1HTR2A | |
| SCHEMBL10424636 | 0.67 | PRSS1 (0.34) | ALDH1A1PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL9793858 | 0.66 | BLM (0.35) | MEN1KMT2ABLMPRSS1CTSG | |
| SCHEMBL7547751 | 0.66 | BLM (0.35) | MEN1KMT2ABLMPRSS1CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993470-B2 | Catalysts for the alkyne metathesis | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2015-03-31 | — | — | US | disclosed |
| US-20130144102-A1 | CATALYSTS FOR THE ALKYNE METATHESIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2013-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130144102-A1 | CATALYSTS FOR THE ALKYNE METATHESIS | MSH6, AP3M1, PMS2 | MEN1 29/4885ALDH1A1 1300/4885KMT2A 1392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.