Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17401199 | 0.90 | GLP1R (0.46) | GLP1RALBFAAHMEN1KMT2A | |
| SCHEMBL15002872 | 0.90 | GLP1R (0.51) | GLP1RALBFOLH1 | |
| SCHEMBL12064338 | 0.85 | GLP1R (0.41) | GLP1RSIRT5ALBFOLH1KDM4E | |
| SCHEMBL13640939 | 0.85 | GLP1R (0.41) | GLP1RSIRT5ALBFOLH1KDM4E | |
| SCHEMBL25651302 | 0.85 | GLP1R (0.45) | GLP1RSIRT5ALBFOLH1KDM4E | |
| SCHEMBL25651306 | 0.83 | GLP1R (0.44) | GLP1RSIRT5ALBFOLH1KDM4E | |
| SCHEMBL18551975 | 0.83 | GLP1R (0.54) | GLP1RSIRT5FOLH1 | |
| SCHEMBL25651303 | 0.81 | GLP1R (0.43) | GLP1RSIRT5ALBFOLH1KDM4E | |
| SCHEMBL25651291 | 0.81 | GLP1R (0.43) | GLP1RSIRT5ALBFOLH1KDM4E | |
| SCHEMBL27310506 | 0.81 | GLP1R (0.48) | GLP1RSIRT5ALBFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130143798-A1 | NOVEL GLUCAGON ANALOGUES | NOVO NORDISK A/S (DK) | 2013-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130143798-A1 | NOVEL GLUCAGON ANALOGUES | GLP1R, GCG, IAPP | GLP1R 1/4885SIRT5 1305/4885ALB 1619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.