SCHEMBL17401199

SCHEMBL17401199

CCC(=O)NCCOCCOCC(=O)NCCCC[C@H](NN)C(N)=O

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.46
▸ MEN1 O00255 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ ALB P02768 1/20 0.34
▸ RECQL P46063 2/20 0.34
▸ FAAH O00519 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ TLR2 O60603 1/20 0.32
▸ CCKAR P32238 1/20 0.32
▸ CCKBR P32239 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12807268 0.90 GLP1R (0.46) GLP1RMEN1KMT2AALBRECQL
SCHEMBL12743611 0.90 GLP1R (0.46) GLP1RMEN1KMT2AALBRECQL
SCHEMBL15002710 0.90 GLP1R (0.44) GLP1RMEN1KMT2AALBFAAH
SCHEMBL14683490 0.85 MEN1 (0.44) GLP1RMEN1KMT2ARECQLFAAH
SCHEMBL17424472 0.83 GLP1R (0.55) GLP1RALBCCKARCCKBR
SCHEMBL14685808 0.83 GLP1R (0.56) GLP1RRECQLFAAHTSHRTLR2
SCHEMBL14685800 0.83 GLP1R (0.46) GLP1RALBFAAHTSHR
SCHEMBL14685801 0.83 GLP1R (0.48) GLP1RMEN1KMT2AALBRECQL
SCHEMBL18551975 0.83 GLP1R (0.54) GLP1RCCKARCCKBR
SCHEMBL14685783 0.81 GLP1R (0.54) GLP1RMEN1KMT2ARECQLFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160002311-A1 Novel Glucagon Analogues NOVO NORDISK AS (DK) 2016-01-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160002311-A1 Novel Glucagon Analogues GLP1R, GIPR, IAPP GLP1R 1/4885MEN1 858/4885KMT2A 4189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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