SCHEMBL25651303

SCHEMBL25651303

CC(=O)NCCOCCOCC(=O)NCCOCCOCC(=O)NCCCC[C@H](NC(C)C)C(=O)C(C)C

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.43
▸ FOLH1 Q04609 4/20 0.36
▸ MEN1 O00255 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ KDM4E B2RXH2 1/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ HIF1A Q16665 1/20 0.34
▸ CPA1 P15085 1/20 0.33
▸ CPA2 P48052 1/20 0.33
▸ CPA4 Q9UI42 1/20 0.33
▸ SIRT5 Q9NXA8 2/20 0.32
▸ FAAH O00519 1/20 0.32
▸ ALB P02768 1/20 0.31
▸ PAOX Q6QHF9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25651291 1.00 GLP1R (0.43) GLP1RFOLH1MEN1KMT2AKDM4E
SCHEMBL25651306 0.93 GLP1R (0.44) GLP1RFOLH1MEN1KMT2AKDM4E
SCHEMBL25651290 0.89 GLP1R (0.43) GLP1RFOLH1MEN1KMT2AKDM4E
SCHEMBL25651309 0.87 GLP1R (0.44) GLP1RFOLH1MEN1KMT2AKDM4E
SCHEMBL12055210 0.83 KDM4E (0.48) FOLH1KDM4EMAPK1HIF1ASIRT5
SCHEMBL16231519 0.83 KDM4E (0.48) FOLH1KDM4EMAPK1HIF1ASIRT5
SCHEMBL25651302 0.83 GLP1R (0.45) GLP1RFOLH1MEN1KMT2AKDM4E
SCHEMBL15002710 0.81 GLP1R (0.44) GLP1RFOLH1MEN1KMT2AKDM4E
SCHEMBL26059788 0.81 GLP1R (0.63) GLP1RFOLH1
SCHEMBL12064338 0.81 GLP1R (0.41) GLP1RFOLH1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230190879-A1 DUAL-AGONIST COMPOUND FOR BOTH GLP-1 AND GIP RECEPTORS AND APPLICATION THEREOF JIANGSU HENGRUI PHARMACEUTICALS CO., LTD. (CN) 2023-06-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230190879-A1 DUAL-AGONIST COMPOUND FOR BOTH GLP-1 AND GIP RECEPTORS AND APPLICATION THEREOF GLP1R, GIPR, GPR119 GLP1R 1/4885FOLH1 692/4885MEN1 1998/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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