Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | CRHBP | P24387 | 2/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8784523 | 0.80 | MAPT (0.69) | MAPTCRHBPCRHR2KMT2AMEN1 | |
| SCHEMBL9886091 | 0.79 | TAAR1 (0.49) | TACR1TAAR1ALDH1A1HPGD | |
| SCHEMBL20286676 | 0.79 | TAAR1 (0.49) | KMT2AL3MBTL1LMNATACR1TAAR1 | |
| SCHEMBL16955939 | 0.76 | TAAR1 (0.46) | KMT2AL3MBTL1LMNATACR1TAAR1 | |
| SCHEMBL29278563 | 0.76 | ALDH1A1 (0.40) | MAPTCRHBPCRHR2KMT2AMEN1 | |
| SCHEMBL3325227 | 0.76 | ESR1 (0.44) | LMNAALDH1A1 | |
| SCHEMBL10361592 | 0.76 | TAAR1 (0.54) | TAAR1 | |
| SCHEMBL12388816 | 0.74 | MAPT (0.56) | MAPTCRHBPCRHR2KMT2AMEN1 | |
| SCHEMBL30463312 | 0.73 | MAPT (0.52) | MAPTCRHBPCRHR2KMT2AMEN1 | |
| SCHEMBL30463311 | 0.73 | MAPT (0.52) | MAPTCRHBPCRHR2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9505878-B2 | Catalysts and methods for polymer synthesis | NOVOMER, INC. (US) | 2016-11-29 | — | — | US | disclosed |
| US-20160272761-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2016-09-22 | — | — | US | disclosed |
| US-9403861-B2 | Salen complexes with dianionic counterions | NOVOMER, INC. (US) | 2016-08-02 | — | — | US | disclosed |
| US-20150252145-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2015-09-10 | — | — | US | disclosed |
| US-8946109-B2 | Catalysts and methods for polymer synthesis | NOVOMER, INC. (US) | 2015-02-03 | — | — | US | disclosed |
| US-20140336354-A1 | SALEN COMPLEXES WITH DIANIONIC COUNTERIONS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2014-11-13 | — | — | US | disclosed |
| US-8633123-B2 | Catalysts and methods for polymer synthesis | NOVOMER, INC. (US) | 2014-01-21 | — | — | US | disclosed |
| US-20130144032-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. (US) | 2013-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140336354-A1 | SALEN COMPLEXES WITH DIANIONIC COUNTERIONS | NCLN, POLN, NCL | MAPT 1373/4885CRHBP 3213/4885CRHR2 3909/4885 |
| US-20130144032-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | PPOX, COASY, SOD1 | MAPT 3940/4885CRHBP 1866/4885CRHR2 2616/4885 |
| US-20160272761-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | PPOX, COASY, SOD1 | MAPT 3940/4885CRHBP 1866/4885CRHR2 2616/4885 |
| US-20150252145-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | PPOX, COASY, SOD1 | MAPT 3940/4885CRHBP 1866/4885CRHR2 2616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.