SCHEMBL1500385

SCHEMBL1500385

CCC(CC(C)=O)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABBR2 O75899 1/20 0.48
GABBR1 Q9UBS5 1/20 0.48
LMNA P02545 3/20 0.47
POLB P06746 1/20 0.47
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 2/20 0.45
MAPT P10636 2/20 0.45
MTNR1A P48039 1/20 0.45
MTNR1B P49286 1/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
HSD17B10 Q99714 2/20 0.44
ALB P02768 1/20 0.44
CYP2C9 P11712 1/20 0.44
PCSK7 Q16549 1/20 0.44
VKORC1 Q9BQB6 1/20 0.44
FFAR1 O14842 1/20 0.44
CCR5 P51681 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
ATM Q13315 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13559962 0.90 GABBR2 (0.53) GABBR2GABBR1KDM4EALDH1A1MAPT
SCHEMBL29110970 0.89 PTGS2 (0.49) ALDH1A1MAPTMEN1KMT2AFFAR1
SCHEMBL240789 0.86 GABBR2 (0.66) GABBR2GABBR1LMNAPOLBKDM4E
SCHEMBL2484805 0.86 GABBR2 (0.66) GABBR2GABBR1LMNAPOLBKDM4E
SCHEMBL6174106 0.86 GABBR2 (0.66) GABBR2GABBR1LMNAPOLBKDM4E
SCHEMBL29110949 0.85 L3MBTL1 (0.50) FFAR1L3MBTL1
SCHEMBL6722503 0.84 GABBR2 (0.48) GABBR2GABBR1LMNAPOLBMAPT
SCHEMBL4445085 0.84 GABBR2 (0.48) GABBR2GABBR1KDM4EALDH1A1MAPT
SCHEMBL9857550 0.84 GABBR2 (0.63) GABBR2GABBR1POLBKDM4EALDH1A1
SCHEMBL17877672 0.82 GABBR2 (0.47) GABBR2GABBR1LMNAPOLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115297728-A Agrochemical compositions of triazoles 阿达玛马克西姆有限公司 2022-11-04 CN claimed
CN-116655459-B Synthetic method for selectively synthesizing 4-aryl-2-hexanone 河南大学 2025-05-09 CN disclosed
CN-116655459-A Synthetic method for selectively synthesizing 4-aryl-2-hexanone 河南大学 2023-08-29 CN disclosed
CN-115297728-A Agrochemical compositions of triazoles 阿达玛马克西姆有限公司 2022-11-04 CN disclosed
EP-2242760-B1 SULFONATED ORGANOPHOSPHINE COMPOUNDS AND USE IN HYDROFORMYLATION PROCESSES DOW GLOBAL TECHNOLOGIES LLC (US) 2014-03-05 EP disclosed
US-8466306-B2 Sulfonated organophosphine compounds and use in hydroformylation processes DOW GLOBAL TECHNOLOGIES LLC (US) 2013-06-18 US disclosed
US-20110054203-A1 SULFONATED ORGANOPHOSPHINE COMPOUNDS AND USE IN HYDROFORMYLATION PROCESSES DOW GLOBAL TECHNOLOGIES INC. (US) 2011-03-03 US disclosed
EP-2242760-A1 SULFONATED ORGANOPHOSPHINE COMPOUNDS AND USE IN HYDROFORMYLATION PROCESSES Dow Global Technologies Inc. (US) 2010-10-27 EP disclosed
WO-2009091669-A1 SULFONATED ORGANOPHOSPHINE COMPOUNDS AND USE IN HYDROFORMYLATION PROCESSES DOW GLOBAL TECHNOLOGIES INC. (US) 2009-07-23 WO disclosed
CN-100400523-C Substituted piperazines, (1,4) diaza * class and 2, 5-diazabicyclo (2.2.1) heptanes as histamine H1 and/or H3 antagonists or histamine H3 reverse antagonists GLAXO GROUP LTD (GB) 2008-07-09 CN disclosed
US-5932771-A PERFUMES SMITHKLINE BEECHAM CORPORATION (US) 1999-08-03 US disclosed
US-5908944-A COPPER COMPOUND CATALYST SCHERING AKTIENGESELLSCHAFT (DE) 1999-06-01 US disclosed
US-5908945-A COPPER COMPOUND AND SILYL REAGENT AS CATALYSTS SCHERING AKTIENGESELLSCHAFT (DE) 1999-06-01 US disclosed
EP-0863864-A1 CARBONYL COMPOUNDS Henkel Kommanditgesellschaft auf Aktien (DE) 1998-09-16 EP disclosed
WO-1997017314-A1 CARBONYL COMPOUNDS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1997-05-15 WO disclosed
EP-0691974-B1 ALKYLATING AGENT AND 1,4-ADDITION PROCESS OF AN ALKYL GROUP ONTO AN ALPHA, BETA-UNSATURATED KETONE COMPOUND SCHERING AG (DE) 1997-05-07 EP disclosed
EP-0534582-B1 Methylation or ethylation agent and process for an 1,4-addition of a methyl- or ethylgroup to an alpha, beta-insaturated ketogroup SCHERING AG (DE) 1997-01-08 EP disclosed
WO-1996039371-A1 AROMATIC CARBONYL COMPOUNDS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1996-12-12 WO disclosed
WO-1993006066-A1 METHYLATING OR ETHYLATING AGENT AND PROCESS FOR 1,4-ADDING A METHYL OR ETHYL GROUP TO AN α,β-UNSATURATED KETO COMPOUND __ SCHERING AKTIENGESELLSCHAFT (DE) 1993-04-01 WO disclosed
EP-0534582-A1 Methylation or ethylation agent and process for an 1,4-addition of a methyl- or ethylgroup to an alpha, beta-insaturated ketogroup SCHERING AKTIENGESELLSCHAFT (DE) 1993-03-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110054203-A1 SULFONATED ORGANOPHOSPHINE COMPOUNDS AND USE IN HYDROFORMYLATION PROCESSES ORMDL3, IP6K3, ALK GABBR2 4332/4885GABBR1 4329/4885LMNA 4629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.