SCHEMBL15020009

SCHEMBL15020009

C=C(C(=O)OC)c1ccc2cc3cc4cc5ccccc5cc4cc3cc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
HPGD P15428 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
ALDH1A1 P00352 2/20 0.49
EGFR P00533 1/20 0.49
TP53 P04637 1/20 0.49
CYP3A4 P08684 1/20 0.49
MAPT P10636 1/20 0.49
PKM P14618 1/20 0.49
ALOX15 P16050 1/20 0.49
ALOX12 P18054 1/20 0.49
JAK1 P23458 1/20 0.49
MAPK1 P28482 1/20 0.49
HSD17B10 Q99714 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
NPC1 O15118 4/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15020198 1.00 KDM4E (0.49) KDM4EMEN1KMT2AHPGDSMN1; SMN2
SCHEMBL28763047 0.95 KDM4E (0.54) KDM4EMEN1KMT2AHPGDSMN1; SMN2
SCHEMBL28989626 0.86 ALDH1A1 (0.59) KDM4EMEN1KMT2AHPGDSMN1; SMN2
SCHEMBL11468589 0.85 KDM4E (0.44) KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL27533543 0.85 MEN1 (0.45) KDM4EMEN1KMT2AHPGDSMN1; SMN2
SCHEMBL28989639 0.84 ALDH1A1 (0.49) KDM4EMEN1KMT2AHPGDSMN1; SMN2
SCHEMBL9301384 0.83 KDM4E (0.62) KDM4EMEN1KMT2AHPGDSMN1; SMN2
SCHEMBL28989643 0.83 ALDH1A1 (0.49) KDM4EMEN1KMT2AHPGDSMN1; SMN2
SCHEMBL11598775 0.82 ALDH1A1 (0.51) KDM4EMEN1KMT2AHPGDSMN1; SMN2
SCHEMBL11469358 0.82 NPC1 (0.41) KDM4EMEN1KMT2AHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2895468-B1 DEVELOPABLE BOTTOM ANTI-REFLECTIVE COATING AZ ELECTRONIC MAT (LUXEMBOURG) S À R L (LU) 2017-10-25 EP disclosed
EP-2895468-A2 DEVELOPABLE BOTTOM ANTI-REFLECTIVE COATING AZ Electronic Materials (Luxembourg) S.à.r.l. (LU) 2015-07-22 EP disclosed
US-8900797-B2 Developable bottom anti-reflective coating AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) 2014-12-02 US disclosed
US-20140193753-A1 COMPOSITION FOR FORMING A DEVELOPABLE BOTTOM ANTIREFLECTIVE COATING AZ ELECTRONIC MATERIALS USA CORP. (US) 2014-07-10 US disclosed
US-8697336-B2 Composition for forming a developable bottom antireflective coating AZ ELECTRONIC MATERIALS USA CORP. (US) 2014-04-15 US disclosed
US-20140087311-A1 DEVELOPABLE BOTTOM ANTI-REFLECTIVE COATING AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (US) 2014-03-27 US disclosed
US-20130157196-A1 COMPOSITION FOR FORMING A DEVELOPABLE BOTTOM ANTIREFLECTIVE COATING AZ ELECTRONIC MATERIALS USA CORP. (US) 2013-06-20 US disclosed
WO-2013089277-A1 COMPOSITION FOR FORMING A DEVELOPABLE BOTTOM ANTI-REFLECTIVE COATING AZ ELECTRONIC MATERIALS IP (JAPAN) K.K. (JP) 2013-06-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140087311-A1 DEVELOPABLE BOTTOM ANTI-REFLECTIVE COATING ALKBH5, METTL14, SETD7 KDM4E 25/4885MEN1 2229/4885KMT2A 276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.