Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | JAK1 | P23458 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isophthalic Acid SCHEMBL6904865 | 0.83 | KMT2A (0.49) | KDM4ESMN1; SMN2ALDH1A1HPGDTP53 | |
| Beta-Naphtoic Acid SCHEMBL27913163 | 0.83 | MEN1 (0.59) | KDM4ESMN1; SMN2ALDH1A1HPGDMEN1 | |
| Benzoic Acid SCHEMBL4217226 | 0.82 | DAO (0.52) | SMN1; SMN2ALDH1A1MEN1TP53MAPT | |
| Terephthalic Acid SCHEMBL6906820 | 0.82 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1TP53MAPT | |
| Beta-Naphtoic Acid SCHEMBL27714607 | 0.81 | KDM4E (0.53) | KDM4ESMN1; SMN2ALDH1A1HPGDMEN1 | |
| Beta-Naphtoic Acid SCHEMBL20518217 | 0.79 | KDM4E (0.67) | KDM4ESMN1; SMN2ALDH1A1HPGDMEN1 | |
| Beta-Naphtoic Acid SCHEMBL727615 | 0.79 | CES2 (0.65) | KDM4ESMN1; SMN2ALDH1A1HPGDMEN1 | |
| Beta-Naphtoic Acid SCHEMBL30678321 | 0.79 | CES2 (0.71) | KDM4ESMN1; SMN2ALDH1A1HPGDMEN1 | |
| Beta-Naphtoic Acid SCHEMBL30678322 | 0.79 | CES2 (0.71) | KDM4ESMN1; SMN2ALDH1A1HPGDMEN1 | |
| Beta-Naphtoic Acid SCHEMBL29628843 | 0.79 | CES2 (0.71) | KDM4ESMN1; SMN2ALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765356-B2 | Calixarene compound and photoresist composition comprising same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-07-01 | — | — | US | disclosed |
| US-20130157195-A1 | CALIXARENE COMPOUND AND PHOTORESIST COMPOSITION COMPRISING SAME | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130157195-A1 | CALIXARENE COMPOUND AND PHOTORESIST COMPOSITION COMPRISING SAME | CALU, UACA, HCAR1 | KDM4E 1976/4885SMN1; SMN2 4563/4885ALDH1A1 107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.