Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 7/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2763103 | 0.87 | NPC1 (0.42) | NPC1RAB9AL3MBTL1MAPTLMNA | |
| SCHEMBL11986854 | 0.85 | HSD17B3 (0.59) | NPC1RAB9AL3MBTL1MAPTLMNA | |
| SCHEMBL9926017 | 0.85 | NPC1 (0.54) | NPC1RAB9AMAPTLMNATDP1 | |
| SCHEMBL1502488 | 0.84 | NPC1 (0.42) | NPC1RAB9AL3MBTL1MAPTLMNA | |
| SCHEMBL3680703 | 0.84 | NPC1 (0.42) | NPC1RAB9AL3MBTL1MAPTLMNA | |
| SCHEMBL1502465 | 0.83 | ALDH1A1 (0.43) | NPC1RAB9AL3MBTL1MAPTLMNA | |
| SCHEMBL4621264 | 0.78 | NPC1 (0.40) | NPC1RAB9AL3MBTL1MAPTLMNA | |
| SCHEMBL8483350 | 0.77 | KMT2A (0.42) | NPC1RAB9AL3MBTL1MAPTLMNA | |
| SCHEMBL19924831 | 0.76 | ALDH1A1 (0.53) | NPC1RAB9AMAPTLMNATDP1 | |
| SCHEMBL7452036 | 0.75 | KMT2A (0.60) | NPC1RAB9AMAPTLMNAHSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289867-A2 | A process for producing 4-(4-halo-1-oxybutyl)-alpha,alpha-dimethylbenzene acetic acid or alkyl esters thereof | Jubilant Organosys Limited (IN) | 2011-03-02 | — | — | EP | disclosed |
| US-20080227983-A1 | PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | AMR TECHNOLOGY, INC. (US) | 2008-09-18 | — | — | US | disclosed |
| US-7390906-B2 | Forming ketone intermediates to terfenadine carboxylic acid metabolite; by use of pure regioisomer of 4-(Cyclopropyl-oxo-methyl)-alpha,alpha-dimethylphenylacetic acid | AMR TECHNOLOGY, INC. (US) | 2008-06-24 | — | — | US | disclosed |
| US-7238834-B2 | Piperidine derivatives and process for their production | AMR TECHNOLOGY, INC. (US) | 2007-07-03 | — | — | US | disclosed |
| US-20060241303-A1 | Piperidine derivatives and process for their production | AMR TECHNOLOGY, INC. (US) | 2006-10-26 | — | — | US | disclosed |
| US-7022880-B2 | Piperidine derivatives and process for their production | AMR TECHNOLOGY , INC. (US) | 2006-04-04 | — | — | US | disclosed |
| US-20060052610-A1 | Piperidine derivatives and process for their production | AMR TECHNOLOGY, INC. (US) | 2006-03-09 | — | — | US | disclosed |
| US-20050020628-A1 | Piperidine derivatives and process for their production | AMR TECHNOLOGY, INC. (US) | 2005-01-27 | — | — | US | disclosed |
| US-6797826-B2 | ACYLATING A STARTING COMPOUND CONTAINING CARBOXY OR AMIDE OR ESTER-ISOPROPYLBENZENE COMPOUND WITH AN CHLOROBUTANOYLHALIDE TO FORM MIXTURE OF REGIOISOMER, HYDROLYZING TO FORM SECOND MIXTURE AND RECOVERING SUBSTANTIALLY PURE RGIOISMOR | AMR TECHNOLOGY, INC. | 2004-09-28 | — | — | US | disclosed |
| EP-1369409-A1 | Process for preparing compounds useful as intermediates | ALBANY MOLECULAR RESEARCH, INC. (US) | 2003-12-10 | — | — | EP | disclosed |
| US-5750703-A | Piperidine derivatives and process for their production | ALBANY MOLECULAR RESEARCH, INC. (US) | 1998-05-12 | — | — | US | disclosed |
| US-5663412-A | Aromatic ketones | ALBANY MOLECULAR RESEARCH, INC. (US) | 1997-09-02 | — | — | US | disclosed |
| US-5589487-A | Piperidine derivatives and process for their production | ALBANY MOLECULAR RESEARCH, INC. (US) | 1996-12-31 | — | — | US | disclosed |
| US-5581011-A | Aromatic ketones and processes for their preparation | ALBANY MOLECULAR RESEARCH, INC. (US) | 1996-12-03 | — | — | US | disclosed |
| US-5578610-A | Piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 1996-11-26 | — | — | US | disclosed |
| US-5569665-A | Peptidyl derivatives and their use as metalloproteinases inhibitors | CELLTECH LIMITED (GB) | 1996-10-29 | — | — | US | disclosed |
| EP-0723958-A1 | Synthesis of substantially pure terfenadine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 1996-07-31 | — | — | EP | disclosed |
| EP-0703902-A4 | — | ALBANY MOLECULAR RES INC (US) | 1996-04-10 | — | — | EP | disclosed |
| EP-0703902-A1 | PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | ALBANY MOLECULAR RESEARCH, INC. (US) | 1996-04-03 | — | — | EP | disclosed |
| WO-1995000482-A1 | PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | ALBANY MOLECULAR RESEARCH, INC. (US) | 1995-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241303-A1 | Piperidine derivatives and process for their production | HRH4, DRD4, H1-4 | NPC1 3145/4885RAB9A 1528/4885L3MBTL1 3895/4885 |
| US-20060052610-A1 | Piperidine derivatives and process for their production | HRH4, DRD4, H1-4 | NPC1 3145/4885RAB9A 1528/4885L3MBTL1 3895/4885 |
| US-20080227983-A1 | PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | HRH4, DRD4, H1-4 | NPC1 3275/4885RAB9A 1485/4885L3MBTL1 3818/4885 |
| US-20050020628-A1 | Piperidine derivatives and process for their production | DRD4, HRH4, H1-4 | NPC1 3293/4885RAB9A 1550/4885L3MBTL1 3821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.