Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | BRS3 | P32247 | 1/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12139296 | 0.91 | ALDH1A1 (0.45) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL4622882 | 0.87 | ALDH1A1 (0.44) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL4686360 | 0.85 | ALDH1A1 (0.43) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL1502354 | 0.85 | ALDH1A1 (0.43) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL1502278 | 0.83 | NPC1 (0.42) | LMNATDP1PDE4BHDAC1HDAC8 | |
| SCHEMBL4960271 | 0.82 | KMT2A (0.53) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL9926017 | 0.81 | NPC1 (0.54) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL28698668 | 0.78 | ALDH1A1 (0.47) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL28370678 | 0.78 | GSK3B (0.54) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL2763103 | 0.77 | NPC1 (0.42) | ALDH1A1LMNARECQLTDP1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289867-A2 | A process for producing 4-(4-halo-1-oxybutyl)-alpha,alpha-dimethylbenzene acetic acid or alkyl esters thereof | Jubilant Organosys Limited (IN) | 2011-03-02 | — | — | EP | disclosed |
| US-7863452-B2 | Process for production of piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 2011-01-04 | — | — | US | disclosed |
| US-7863452-B2 | Process for production of piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 2011-01-04 | — | — | US | disclosed |
| US-20090124810-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 2009-05-14 | — | — | US | disclosed |
| US-20090124810-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 2009-05-14 | — | — | US | disclosed |
| US-7498345-B2 | Process for production of piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 2009-03-03 | — | — | US | disclosed |
| US-7498345-B2 | Process for production of piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 2009-03-03 | — | — | US | disclosed |
| US-20080227983-A1 | PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | AMR TECHNOLOGY, INC. (US) | 2008-09-18 | — | — | US | disclosed |
| US-7390906-B2 | Forming ketone intermediates to terfenadine carboxylic acid metabolite; by use of pure regioisomer of 4-(Cyclopropyl-oxo-methyl)-alpha,alpha-dimethylphenylacetic acid | AMR TECHNOLOGY, INC. (US) | 2008-06-24 | — | — | US | disclosed |
| US-7238834-B2 | Piperidine derivatives and process for their production | AMR TECHNOLOGY, INC. (US) | 2007-07-03 | — | — | US | disclosed |
| EP-0703902-B1 | PROCESS FOR THE PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RES INC (US) | 1998-12-16 | — | — | EP | disclosed |
| US-5750703-A | Piperidine derivatives and process for their production | ALBANY MOLECULAR RESEARCH, INC. (US) | 1998-05-12 | — | — | US | disclosed |
| US-5663412-A | Aromatic ketones | ALBANY MOLECULAR RESEARCH, INC. (US) | 1997-09-02 | — | — | US | disclosed |
| US-5589487-A | Piperidine derivatives and process for their production | ALBANY MOLECULAR RESEARCH, INC. (US) | 1996-12-31 | — | — | US | disclosed |
| US-5581011-A | Aromatic ketones and processes for their preparation | ALBANY MOLECULAR RESEARCH, INC. (US) | 1996-12-03 | — | — | US | disclosed |
| US-5578610-A | Piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 1996-11-26 | — | — | US | disclosed |
| EP-0723958-A1 | Synthesis of substantially pure terfenadine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 1996-07-31 | — | — | EP | disclosed |
| EP-0703902-A4 | — | ALBANY MOLECULAR RES INC (US) | 1996-04-10 | — | — | EP | disclosed |
| EP-0703902-A1 | PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | ALBANY MOLECULAR RESEARCH, INC. (US) | 1996-04-03 | — | — | EP | disclosed |
| WO-1995000482-A1 | PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | ALBANY MOLECULAR RESEARCH, INC. (US) | 1995-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124810-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | HADHB, CPT1B, PDHB | ALDH1A1 84/4885LMNA 2598/4885ALOX15 3446/4885 |
| US-20080227983-A1 | PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | HRH4, DRD4, H1-4 | ALDH1A1 302/4885LMNA 4278/4885ALOX15 3319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.