Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 4/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1502278 | 0.85 | NPC1 (0.42) | NPC1RAB9AMAPTLMNATDP1 | |
| SCHEMBL2763103 | 0.85 | NPC1 (0.42) | NPC1RAB9AMAPTLMNAALDH1A1 | |
| SCHEMBL7079689 | 0.85 | RAB9A (0.66) | NPC1RAB9AMAPTLMNAALDH1A1 | |
| SCHEMBL7885323 | 0.84 | HSD17B3 (0.65) | NPC1RAB9AMAPTLMNAALDH1A1 | |
| SCHEMBL4621264 | 0.82 | NPC1 (0.40) | NPC1RAB9AMAPTLMNATDP1 | |
| SCHEMBL2240591 | 0.82 | NPC1 (0.54) | NPC1RAB9AMAPTLMNAALDH1A1 | |
| SCHEMBL1502465 | 0.81 | ALDH1A1 (0.43) | NPC1RAB9AMAPTLMNAALDH1A1 | |
| SCHEMBL14302682 | 0.81 | HSD17B3 (0.67) | NPC1RAB9AMAPTALDH1A1HDAC1 | |
| SCHEMBL10471647 | 0.81 | MAPT (0.53) | NPC1RAB9AMAPTLMNAALDH1A1 | |
| SCHEMBL10471481 | 0.81 | NPC1 (0.53) | NPC1RAB9AMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076919-A1 | PROCESS OF PREPARING EBASTINE | MICRO LABS LIMITED (IN) | 2012-06-14 | — | — | WO | disclosed |