Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | USP5 | P45974 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3628597 | 0.85 | RAB9A (0.54) | KMT2ARAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL7038376 | 0.81 | RORC (0.40) | KMT2ARAB9ANPC1MAPTLMNA | |
| SCHEMBL11986854 | 0.79 | HSD17B3 (0.59) | RAB9ANPC1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL2861170 | 0.78 | MMP1 (0.58) | MAPTNR4A2ALDH1A1MMP1SRD5A2 | |
| SCHEMBL3680703 | 0.77 | NPC1 (0.42) | RAB9ANPC1MAPTL3MBTL1LMNA | |
| SCHEMBL1502278 | 0.77 | NPC1 (0.42) | KMT2ARAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL1502488 | 0.77 | NPC1 (0.42) | KMT2ARAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL19924831 | 0.76 | ALDH1A1 (0.53) | KMT2ARAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL2118360 | 0.75 | KMT2A (0.66) | KMT2ARAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL276676 | 0.75 | NR4A2 (0.65) | KMT2ARAB9ANPC1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925761-A | Synthesis of terfenadine and derivatives | SEPRACOR INC. (US) | 1999-07-20 | — | — | US | disclosed |