Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 6/20 | 0.58 |
| ▸ | THRA | P10827 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12440971 | 0.91 | MEN1 (0.55) | THRBTHRAMAPTGAAHPGD | |
| SCHEMBL13429977 | 0.89 | THRB (0.48) | THRBTHRAMAPTGAAHPGD | |
| SCHEMBL12514358 | 0.87 | THRA (0.50) | THRBTHRAMAPTGAAHPGD | |
| SCHEMBL19732195 | 0.87 | MAPT (0.58) | THRBTHRAMAPTGAATDP1 | |
| SCHEMBL13508902 | 0.87 | THRB (0.47) | THRBTHRAMAPTGAAHPGD | |
| SCHEMBL9946070 | 0.86 | THRB (0.46) | THRBTHRAMAPTGAAHPGD | |
| SCHEMBL13508900 | 0.86 | THRB (0.46) | THRBTHRAMAPTGAAHPGD | |
| SCHEMBL5083962 | 0.86 | THRB (0.46) | THRBTHRAMAPTGAAHPGD | |
| SCHEMBL13429711 | 0.86 | THRB (0.46) | THRBTHRAMAPTGAAHPGD | |
| SCHEMBL3317609 | 0.86 | LIPE (0.50) | THRBTHRAMAPTGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2473538-B1 | CATALYST AND PROCESS FOR POLYMERIZING AN OLEFIN AND POLYOLEFIN PREPARED THEREBY | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-07-26 | — | — | EP | disclosed |
| EP-2473538-B1 | CATALYST AND PROCESS FOR POLYMERIZING AN OLEFIN AND POLYOLEFIN PREPARED THEREBY | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-07-26 | — | — | EP | disclosed |
| EP-2473538-A1 | CATALYST AND PROCESS FOR POLYMERIZING AN OLEFIN AND POLYOLEFIN PREPARED THEREBY | Dow Global Technologies LLC (US) | 2012-07-11 | — | — | EP | disclosed |
| US-20110054122-A1 | CATALYST AND PROCESS FOR POLYMERIZING AN OLEFIN AND POLYOLEFIN PREPARED THEREBY | DOW GLOBAL TECHNOLOGIES LLC | 2011-03-03 | — | — | US | disclosed |
| US-20110054122-A1 | CATALYST AND PROCESS FOR POLYMERIZING AN OLEFIN AND POLYOLEFIN PREPARED THEREBY | DOW GLOBAL TECHNOLOGIES LLC | 2011-03-03 | — | — | US | disclosed |
| WO-2011025784-A1 | CATALYST AND PROCESS FOR POLYMERIZING AN OLEFIN AND POLYOLEFIN PREPARED THEREBY | DOW GLOBAL TECHNOLOGIES INC. (US) | 2011-03-03 | — | — | WO | disclosed |
| EP-1501840-B1 | BRIDGED BI-AROMATIC LIGANDS, COMPLEXES, CATALYSTS, PROCESSES FOR POLYMERIZING AND POLYMERS THEREFROM | SYMYX SOLUTIONS INC (US) | 2010-12-22 | — | — | EP | disclosed |
| US-7659415-B2 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | SYMYX SOLUTIONS, INC. (US) | 2010-02-09 | — | — | US | disclosed |
| US-7659415-B2 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | SYMYX SOLUTIONS, INC. (US) | 2010-02-09 | — | — | US | disclosed |
| US-20080269470-A1 | Bridged Bi-Aromatic Ligands, Catalysts, Processes For Polymerizing And Polymers Therefrom | SYMYX TECHNOLOGIES, INC. (US) | 2008-10-30 | — | — | US | disclosed |
| US-20050164872-A1 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | SYMYX TECHNOLOGIES, INC. | 2005-07-28 | — | — | US | disclosed |
| US-6897276-B2 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | SYMYX TECHNOLOGIES, INC. (US) | 2005-05-24 | — | — | US | disclosed |
| US-20050080281-A1 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | SYMYX TECHNOLOGIES, INC. | 2005-04-14 | — | — | US | disclosed |
| US-6869904-B2 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | SYMYX TECHNOLOGIES, INC. (US) | 2005-03-22 | — | — | US | disclosed |
| EP-1501840-A1 | BRIDGED BI-AROMATIC LIGANDS, COMPLEXES, CATALYSTS AND PROCESSES FOR POLYMERIZING AND POLYMERS THEREFROM | Symyx Technologies, Inc. (US) | 2005-02-02 | — | — | EP | disclosed |
| US-6841502-B2 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | SYMYX TECHNOLOGIES, INC. (US) | 2005-01-11 | — | — | US | disclosed |
| US-20040014950-A1 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | SYMYX TECHNOLOGIES, INC. (US) | 2004-01-22 | — | — | US | disclosed |
| US-20040010103-A1 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | SYMYX TECHNOLOGIES, INC. | 2004-01-15 | — | — | US | disclosed |
| US-20040005984-A1 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | SYMYX TECHNOLOGIES, INC. | 2004-01-08 | — | — | US | disclosed |
| WO-2003091262-A1 | BRIDGED BI-AROMATIC LIGANDS, COMPLEXES, CATALYSTS AND PROCESSES FOR POLYMERIZING AND POYMERS THEREFROM | SYMYX TECHNOLOGIES, INC. (US) | 2003-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014950-A1 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | WEE1, WASF2, WEE2 | THRB 3204/4885THRA 3478/4885MAPT 779/4885 |
| US-20080269470-A1 | Bridged Bi-Aromatic Ligands, Catalysts, Processes For Polymerizing And Polymers Therefrom | WEE1, WASF2, WEE2 | THRB 3204/4885THRA 3478/4885MAPT 779/4885 |
| US-20050164872-A1 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | WEE1, WASF2, WEE2 | THRB 3077/4885THRA 3201/4885MAPT 769/4885 |
| US-20050080281-A1 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | WEE1, WASF2, WEE2 | THRB 3204/4885THRA 3478/4885MAPT 779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.