SCHEMBL1502383

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3633425	0.90	CHEK1 (0.48)	HPGDKDM4ECHEK1ALDH1A1GAA
	SCHEMBL1502385	0.83	KDM4E (0.52)	HPGDKDM4ECHEK1HTR4ALDH1A1
	SCHEMBL1501969	0.83	HTR4 (0.66)	KDM4EHTR4ADRA2CALDH1A1CYP1A2
	Hydrochloric Acid SCHEMBL9021789	0.82	HTR4 (0.65)	KDM4EHTR4
	SCHEMBL7991765	0.78	HTR4 (0.64)	KDM4EHTR4
	SCHEMBL1501974	0.76	CHEK1 (0.44)	HPGDKDM4ECHEK1ALDH1A1POLB
	SCHEMBL1502177	0.76	CHEK1 (0.44)	HPGDKDM4ECHEK1HTR4ALDH1A1
	SCHEMBL13162864	0.75	CHEK1 (0.56)	HPGDKDM4ECHEK1ALDH1A1HSD17B10
	SCHEMBL1753594	0.74	MKNK2 (0.50)	HPGDKDM4ECHEK1ADRA2CALDH1A1
	SCHEMBL1502335	0.73	HTR1A (0.47)	HPGDKDM4ECHEK1HTR4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.