Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.50 |
| ▸ | DGKA | P23743 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.45 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.45 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.45 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.45 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15027020 | 1.00 | EPHX2 (0.50) | EPHX2DNM1DGKAFAAHTSHR | |
| SCHEMBL15026968 | 1.00 | EPHX2 (0.50) | EPHX2DNM1DGKAFAAHTSHR | |
| SCHEMBL15026922 | 0.99 | DNM1 (0.51) | EPHX2DNM1DGKAFAAHTSHR | |
| SCHEMBL21426280 | 0.94 | DGKA (0.51) | EPHX2DGKAFAAHTSHRLPAR1 | |
| SCHEMBL25788524 | 0.91 | PRKCA (0.50) | EPHX2DNM1DGKAFAAHLPAR1 | |
| SCHEMBL15027026 | 0.91 | DNM1 (0.57) | EPHX2DNM1DGKAFAAHLPAR1 | |
| SCHEMBL25788495 | 0.89 | PRKCA (0.48) | EPHX2DNM1DGKAFAAHLPAR1 | |
| SCHEMBL16172063 | 0.88 | DNM1 (0.42) | EPHX2DNM1DGKALPAR1PRKCE | |
| SCHEMBL14239784 | 0.88 | DNM1 (0.63) | EPHX2DNM1DGKAFAAHLPAR1 | |
| SCHEMBL17586403 | 0.88 | DNM1 (0.63) | EPHX2DNM1DGKAFAAHLPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140308304-A1 | LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | ALNYLAM PHARMACEUTICALS, INC. | 2014-10-16 | — | — | US | disclosed |
| US-20140308304-A1 | LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | ALNYLAM PHARMACEUTICALS, INC. | 2014-10-16 | — | — | US | disclosed |
| WO-2013086373-A1 | LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2013-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140308304-A1 | LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | NPC1L1, NPC1, CETP | EPHX2 2530/4885DNM1 241/4885DGKA 394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.