Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
| ▸ | PDE6D | O43924 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15030670 | 0.90 | PDK2 (0.35) | PDK2TYMSPDE6D | |
| SCHEMBL15030887 | 0.89 | PDK2 (0.35) | PDK2BACE1 | |
| SCHEMBL16186708 | 0.85 | — | — | |
| SCHEMBL15213627 | 0.84 | PDK2 (0.37) | PDK2TYMSPDE6D | |
| SCHEMBL15030695 | 0.83 | BACE1 (0.31) | BACE1 | |
| SCHEMBL25121505 | 0.83 | PDE6D (0.33) | PDK2PDE6D | |
| SCHEMBL15030800 | 0.83 | PDK2 (0.36) | PDK2BACE1 | |
| SCHEMBL16810737 | 0.82 | PDK2 (0.36) | PDK2TYMSPDE6D | |
| SCHEMBL17816797 | 0.82 | PDK2 (0.36) | PDK2TYMSPDE6D | |
| SCHEMBL19001836 | 0.81 | PDK2 (0.38) | PDK2TYMSPDE6D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10396297-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2019-08-27 | — | — | US | disclosed |
| US-10305040-B2 | Spiro dihydroacridine derivatives and the use thereof as materials for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2019-05-28 | — | — | US | disclosed |
| US-20170331053-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-11-16 | — | — | US | disclosed |
| US-20170331053-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-11-16 | — | — | US | disclosed |
| EP-2780325-B1 | SPIRO-DIHYDROACRIDINE DERIVATIVES AND THEIR USE AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-02-03 | — | — | EP | disclosed |
| US-20140316134-A1 | SPIRO DIHYDROACRIDINE DERIVATIVES AND THE USE THEREOF AS MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-10-23 | — | — | US | disclosed |
| US-20140316134-A1 | SPIRO DIHYDROACRIDINE DERIVATIVES AND THE USE THEREOF AS MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-10-23 | — | — | US | disclosed |
| WO-2013083216-A1 | SPIRO DIHYDROACRIDINE DERIVATIVES AND THE USE THEREOF AS MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2013-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10305040-B2 | Spiro dihydroacridine derivatives and the use thereof as materials for organic electroluminescence devices | SORD, ALDH1A1, SDHA | PDK2 202/4885TYMS 516/4885PDE6D 125/4885 |
| US-10396297-B2 | Materials for electronic devices | DDT, PNMT, COMT | PDK2 413/4885TYMS 2743/4885PDE6D 1445/4885 |
| US-20170331053-A1 | MATERIALS FOR ELECTRONIC DEVICES | DDT, PNMT, COMT | PDK2 413/4885TYMS 2743/4885PDE6D 1445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.