Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.51 |
| ▸ | VNN1 | O95497 | 3/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | NNMT | P40261 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29567644 | 0.79 | VNN1 (0.55) | HPGDSVNN1PARP10PARP1CA1 | |
| SCHEMBL29056033 | 0.78 | GRM2 (0.47) | PARP10PARP1CA1CA2PARP2 | |
| SCHEMBL27858247 | 0.77 | CYP19A1 (0.47) | CA1CA2CHEK2POLB | |
| SCHEMBL27915062 | 0.77 | PARP10 (0.56) | VNN1PARP10PARP1CA1CA2 | |
| SCHEMBL28349713 | 0.77 | PARP10 (0.56) | VNN1PARP10PARP1CA1CA2 | |
| SCHEMBL30478243 | 0.75 | NNMT (0.41) | HPGDSPARP10PARP1NNMT | |
| SCHEMBL8213818 | 0.75 | PARP10 (0.78) | VNN1PARP10PARP1CA1CA2 | |
| SCHEMBL28285907 | 0.75 | NNMT (0.41) | HPGDSPARP10PARP1NNMT | |
| SCHEMBL28127922 | 0.74 | PARP10 (0.59) | VNN1PARP10PARP1CA1CA2 | |
| SCHEMBL4001952 | 0.74 | PARP10 (0.56) | VNN1PARP10PARP1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300433-A1 | HIV INTEGRASE INHIBITORS FROM PYRIDOXINE | Ambrilia Biopharma Inc. (CA) | 2011-03-30 | — | — | EP | disclosed |