Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRE | P78334 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28285907 | 1.00 | NNMT (0.41) | NNMTSMN1; SMN2HPGDSTSHRGABRP | |
| SCHEMBL1503085 | 0.85 | NNMT (0.40) | NNMTSMN1; SMN2HPGDSLMNAPSMD14 | |
| SCHEMBL840723 | 0.80 | NNMT (0.36) | NNMTSMN1; SMN2HPGDSPSMD14STAMBP | |
| SCHEMBL31086582 | 0.77 | MTNR1B (0.41) | NNMTHPGDSLMNAPARP10PARP1 | |
| SCHEMBL2219734 | 0.77 | NNMT (0.46) | NNMTSMN1; SMN2HPGDSLMNAPSMD14 | |
| SCHEMBL19857467 | 0.76 | MAPT (0.43) | SMN1; SMN2GABRPGABRDGABRA1GABRB1 | |
| Hydrochloric Acid SCHEMBL28641941 | 0.76 | NNMT (0.44) | NNMTSMN1; SMN2HPGDSLMNAPSMD14 | |
| SCHEMBL1503082 | 0.75 | HPGDS (0.51) | NNMTHPGDSPARP10PARP1 | |
| SCHEMBL30617860 | 0.75 | HPGDS (0.36) | NNMTSMN1; SMN2HPGDSPARP10PSMD14 | |
| SCHEMBL2397267 | 0.75 | NNMT (0.44) | NNMTSMN1; SMN2HPGDSLMNAPSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354992-A | PDE4 inhibitor and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-116354931-A | Substituted oxazole derivative and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-30 | — | — | CN | disclosed |