Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 2/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10801178 | 0.87 | LMNA (0.34) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL13816869 | 0.77 | TRPA1 (0.35) | TRPA1AR | |
| SCHEMBL13097699 | 0.76 | AR (0.56) | AR | |
| SCHEMBL16960221 | 0.75 | GABRA1 (0.41) | TRPA1LMNASLC6A2ADRA1AHTR2B | |
| SCHEMBL16259534 | 0.74 | SLC9A1 (0.35) | — | |
| SCHEMBL12154091 | 0.74 | CYP1A2 (0.33) | AR | |
| SCHEMBL17947171 | 0.72 | PDE2A (0.39) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL10938436 | 0.72 | LMNA (0.39) | GPR55TRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL12604305 | 0.71 | LMNA (0.35) | GPR55TRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL13199206 | 0.71 | AR (0.41) | ARPDE2APDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466171-B2 | Fused heterocyclic compounds useful as modulators of nuclear hormone receptor function | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-06-18 | — | — | US | disclosed |