Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 1.00 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 1.00 |
| ▸ | RECQL | P46063 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | S100A4 | P26447 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8371904 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSP90AA1HSP90AB1RECQLL3MBTL1 | |
| SCHEMBL13703352 | 0.78 | ALDH1A1 (0.62) | ALDH1A1HSP90AA1HSP90AB1RECQLL3MBTL1 | |
| SCHEMBL6796515 | 0.72 | ALDH1A1 (0.56) | ALDH1A1HSP90AA1HSP90AB1RECQLL3MBTL1 | |
| SCHEMBL11136806 | 0.72 | ALDH1A1 (0.70) | ALDH1A1HSP90AA1HSP90AB1RECQLL3MBTL1 | |
| SCHEMBL25698875 | 0.70 | ALDH1A1 (0.53) | ALDH1A1HSP90AA1HSP90AB1RECQLL3MBTL1 | |
| SCHEMBL10869632 | 0.69 | ALDH1A1 (0.52) | ALDH1A1HSP90AA1HSP90AB1RECQLL3MBTL1 | |
| SCHEMBL30982233 | 0.68 | CA1 (0.70) | ALDH1A1HSP90AA1HSP90AB1RECQLL3MBTL1 | |
| SCHEMBL29023321 | 0.68 | CA1 (0.56) | ALDH1A1HSP90AA1HSP90AB1RECQLL3MBTL1 | |
| SCHEMBL3658029 | 0.67 | CA1 (1.00) | ALDH1A1HSP90AA1HSP90AB1RECQLL3MBTL1 | |
| SCHEMBL208765 | 0.67 | ALDH1A1 (0.70) | ALDH1A1HSP90AA1HSP90AB1RECQLL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9073941-B2 | Compounds and methods for treating tuberculosis infection | ACADEMIA SINICA (TW) | 2015-07-07 | — | — | US | disclosed |
| US-9073941-B2 | Compounds and methods for treating tuberculosis infection | ACADEMIA SINICA (TW) | 2015-07-07 | — | — | US | disclosed |
| US-20130158037-A1 | COMPOUNDS AND METHODS FOR TREATING TUBERCULOSIS INFECTION | ACADEMIA SINICA (TW) | 2013-06-20 | — | — | US | disclosed |
| US-20130158037-A1 | COMPOUNDS AND METHODS FOR TREATING TUBERCULOSIS INFECTION | ACADEMIA SINICA (TW) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158037-A1 | COMPOUNDS AND METHODS FOR TREATING TUBERCULOSIS INFECTION | TALDO1, PGD, DLD | ALDH1A1 674/4885HSP90AA1 3725/4885HSP90AB1 3132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.