Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL825977 | 0.83 | HRH3 (0.48) | HRH3GNAO1MAOAMAOB | |
| SCHEMBL25075199 | 0.77 | HRH3 (0.35) | HRH3 | |
| SCHEMBL25725586 | 0.75 | PIK3CD (0.37) | HRH3 | |
| SCHEMBL26501021 | 0.74 | PIK3CD (0.36) | HRH3 | |
| SCHEMBL13512410 | 0.73 | PIK3CD (0.39) | HRH3GNAO1MAOAMAOB | |
| SCHEMBL13967023 | 0.70 | GNAO1 (0.42) | HRH3GNAO1 | |
| SCHEMBL25075442 | 0.70 | HRH3 (0.39) | HRH3 | |
| SCHEMBL102108 | 0.70 | HRH3 (0.41) | HRH3GNAO1MAOAMAOB | |
| SCHEMBL27357785 | 0.69 | HRH3 (0.55) | HRH3GNAO1 | |
| SCHEMBL25075448 | 0.69 | HRH3 (0.38) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130150404-A1 | BIPHENYL DERIVATIVES | THERAVANCE, INC. (US) | 2013-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150404-A1 | BIPHENYL DERIVATIVES | ADRB1, ADRB2, ADRB3 | HRH3 78/4885GNAO1 434/4885MAOA 555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.