Diphenylmethane

Diphenylmethane

SCHEMBL15033700

CN(C)c1ccc(Cc2ccccc2)cc1.c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.81

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.81
TSHR P16473 3/20 0.81
MAPK1 P28482 2/20 0.81
TDP1 Q9NUW8 2/20 0.81
CYP3A4 P08684 1/20 0.81
CALM1 P0DP23 1/20 0.57
CHKA P35790 3/20 0.53
LMNA P02545 2/20 0.53
HTT P42858 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
HSD17B10 Q99714 2/20 0.52
ALOX15 P16050 1/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
HDAC1 Q13547 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52
LTA4H P09960 2/20 0.50
RELA Q04206 1/20 0.50
HPGD P15428 2/20 0.49
G6PC1 P35575 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5580184 1.00 ALDH1A1 (0.81) ALDH1A1TSHRMAPK1TDP1CYP3A4
Hydrochloric Acid SCHEMBL8030257 0.98 ALDH1A1 (0.77) ALDH1A1TSHRMAPK1TDP1CYP3A4
SCHEMBL76217 0.90 ALDH1A1 (1.00) ALDH1A1TSHRMAPK1TDP1CYP3A4
SCHEMBL12679051 0.90 ALDH1A1 (1.00) ALDH1A1TSHRMAPK1TDP1CYP3A4
Oxalic Acid SCHEMBL4586651 0.90 ALDH1A1 (0.65) ALDH1A1TSHRMAPK1TDP1CYP3A4
Toluene SCHEMBL10908243 0.89 ALDH1A1 (0.71) ALDH1A1TSHRMAPK1TDP1CYP3A4
Hydrochloric Acid SCHEMBL1450346 0.87 ALDH1A1 (0.94) ALDH1A1TSHRMAPK1TDP1CYP3A4
SCHEMBL20169472 0.86 ALDH1A1 (0.58) ALDH1A1TSHRMAPK1TDP1CYP3A4
SCHEMBL10534118 0.86 ALDH1A1 (0.58) ALDH1A1TSHRMAPK1TDP1CYP3A4
SCHEMBL11019084 0.85 ALDH1A1 (0.71) ALDH1A1TSHRMAPK1TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8932787-B2 Electrophotographic photoconductor, electrophotographic apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2015-01-13 US disclosed
US-8932787-B2 Electrophotographic photoconductor, electrophotographic apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2015-01-13 US disclosed
US-20130157181-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, ELECTROPHOTOGRAPHIC APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-06-20 US disclosed
US-20130157181-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, ELECTROPHOTOGRAPHIC APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-06-20 US disclosed