Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 known ✓ | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC6 known ✓ | Q9UBN7 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.94 |
| ▸ | TSHR | P16473 | 4/20 | 0.94 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.94 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.94 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.94 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12679051 | 0.97 | ALDH1A1 (1.00) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL76217 | 0.97 | ALDH1A1 (1.00) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| Hydrochloric Acid SCHEMBL8030257 | 0.91 | ALDH1A1 (0.77) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL10932875 | 0.90 | ALDH1A1 (0.85) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL14018284 | 0.90 | ALDH1A1 (0.85) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL13821789 | 0.87 | ALDH1A1 (0.81) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| Methane SCHEMBL2520492 | 0.87 | ALDH1A1 (0.81) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| Diphenylmethane SCHEMBL15033700 | 0.87 | ALDH1A1 (0.81) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL5580184 | 0.87 | ALDH1A1 (0.81) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL15488868 | 0.87 | ALDH1A1 (0.81) | ALDH1A1TSHRCYP3A4MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11021538-A | — | — | None | — | — | JP | disclosed |
| US-20130280438-A1 | METHOD FOR PRODUCING POLARIZING FILM, AND LIQUID CRYSTAL DISPLAY DEVICE | NITTO DENKO CORPORATION (JP) | 2013-10-24 | — | — | US | disclosed |
| US-8021572-B2 | Optical laminate, polarizing plate, image display, and process for producing an optical laminate | NITTO DENKO CORPORATION (JP) | 2011-09-20 | — | — | US | disclosed |
| US-8009267-B2 | Method of producing optical laminate and image displaying apparatus | NITTO DENKO CORPORATION (JP) | 2011-08-30 | — | — | US | disclosed |
| US-7911569-B2 | Method of producing optical laminate and image displaying apparatus | NITTO DENKO CORPORATION (JP) | 2011-03-22 | — | — | US | disclosed |
| US-7850868-B2 | Lyotropic liquid crystalline mixture, coating liquid, and optical anisotropic film | NITTO DENKO CORPORATION (JP) | 2010-12-14 | — | — | US | disclosed |
| US-20100220271-A1 | METHOD OF PRODUCING OPTICAL LAMINATE AND IMAGE DISPLAYING APPARATUS | NITTO DENKO CORPORATION (JP) | 2010-09-02 | — | — | US | disclosed |
| US-20100165284-A1 | METHOD OF PRODUCING OPTICAL LAMINATE AND IMAGE DISPLAYING APPARATUS | NITTO DENKO CORPORATION (JP) | 2010-07-01 | — | — | US | disclosed |
| US-7736707-B2 | Birefringent film, polycyclic compound, coating liquid, and image display device | NITTO DENKO CORPORATION (JP) | 2010-06-15 | — | — | US | disclosed |
| US-20100128211-A1 | BIREFRINGENT FILM, LAMINATED FILM, AND IMAGE DISPLAY DEVICE | NITTO DENKO CORPORATION (JP) | 2010-05-27 | — | — | US | disclosed |
| US-7638611-B2 | Polarizer, coating liquid, and manufacturing method for polarizer | NITTO DENKO CORPORATION (JP) | 2009-12-29 | — | — | US | disclosed |
| US-20090187012-A1 | POLARIZER, COATING LIQUID, AND MANUFACTURING METHOD FOR POLARIZER | NITTO DENKO CORPORATION (JP) | 2009-07-23 | — | — | US | disclosed |
| US-20090168000-A1 | LIQUID CRYSTAL PANEL AND LIQUID CRYSTAL DISPLAY APPARATUS | NITTO DENKO CORPORATION (JP) | 2009-07-02 | — | — | US | disclosed |
| US-20090103029-A1 | LIQUID CRYSTAL PANEL AND LIQUID CRYSTAL DISPLAY APPARATUS | NITTO DENKO CORPORATION (JP) | 2009-04-23 | — | — | US | disclosed |
| US-20090027597-A1 | METHOD FOR PRODUCING POLARIZING FILM, AND LIQUID CRYSTAL DISPLAY DEVICE | NITTO DENKO CORPORATION (JP) | 2009-01-29 | — | — | US | disclosed |
| EP-2012178-A1 | LIQUID CRYSTAL PANEL AND LIQUID CRYSTAL DISPLAY DEVICE | Nitto Denko Corporation (JP) | 2009-01-07 | — | — | EP | disclosed |
| US-20080224095-A1 | BIREFRINGENT FILM, POLYCYCLIC COMPOUND, COATING LIQUID, AND IMAGE DISPLAY DEVICE | NITTO DENKO CORPORATION (JP) | 2008-09-18 | — | — | US | disclosed |
| EP-1881351-A1 | METHOD FOR PRODUCTION OF POLARIZING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT | Nitto Denko Corporation (JP) | 2008-01-23 | — | — | EP | disclosed |
| JP-H1121538-A | ORGANIC THIN FILM | NIPPON KAYAKU CO LTD | 1999-01-26 | — | — | JP | disclosed |
| US-4370312-A | HAPTENS, TRACERS, ANTIBODIES AND STARTING MATERIALS FOR INTERFERONS | Dr. Karl Thomae Gesellshaft mit beschrankter Haftung (DE) | 1983-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080224095-A1 | BIREFRINGENT FILM, POLYCYCLIC COMPOUND, COATING LIQUID, AND IMAGE DISPLAY DEVICE | CIAPIN1, PYM1, AQP1 | HDAC1 3026/4885HDAC6 4428/4885ALDH1A1 3699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.