Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.57 |
| ▸ | CHKA | P35790 | 4/20 | 0.50 |
| ▸ | LTA4H | P09960 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18873551 | 0.98 | TSHR (0.56) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL17904039 | 0.94 | CHKA (0.54) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL28318832 | 0.92 | CYP2C19 (0.55) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL17904029 | 0.92 | CHKA (0.57) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL22183146 | 0.88 | CHKA (0.50) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL21987885 | 0.87 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL17904094 | 0.87 | CHKA (0.53) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| Diphenylmethane SCHEMBL15033700 | 0.86 | ALDH1A1 (0.81) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL5580184 | 0.86 | ALDH1A1 (0.81) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL13020864 | 0.84 | ALDH1A1 (0.63) | ALDH1A1TSHRCYP3A4MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200212301-A1 | SPIROBIFLUORENE DERIVATIVES FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-07-02 | — | — | US | disclosed |
| US-9978949-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2018-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200212301-A1 | SPIROBIFLUORENE DERIVATIVES FOR USE IN ELECTRONIC DEVICES | SELE, KCNB2, SCNN1B | ALDH1A1 21/4885TSHR 2633/4885CYP3A4 298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.