SCHEMBL5580184

SCHEMBL5580184

CN(C)c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.81
TSHR P16473 3/20 0.81
MAPK1 P28482 2/20 0.81
TDP1 Q9NUW8 2/20 0.81
CYP3A4 P08684 1/20 0.81
CALM1 P0DP23 1/20 0.57
CHKA P35790 3/20 0.53
LMNA P02545 2/20 0.53
HTT P42858 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
HSD17B10 Q99714 2/20 0.52
ALOX15 P16050 1/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
HDAC1 Q13547 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52
LTA4H P09960 2/20 0.50
RELA Q04206 1/20 0.50
HPGD P15428 2/20 0.49
G6PC1 P35575 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylmethane SCHEMBL15033700 1.00 ALDH1A1 (0.81) ALDH1A1TSHRMAPK1TDP1CYP3A4
Hydrochloric Acid SCHEMBL8030257 0.98 ALDH1A1 (0.77) ALDH1A1TSHRMAPK1TDP1CYP3A4
SCHEMBL76217 0.90 ALDH1A1 (1.00) ALDH1A1TSHRMAPK1TDP1CYP3A4
SCHEMBL12679051 0.90 ALDH1A1 (1.00) ALDH1A1TSHRMAPK1TDP1CYP3A4
Oxalic Acid SCHEMBL4586651 0.90 ALDH1A1 (0.65) ALDH1A1TSHRMAPK1TDP1CYP3A4
Toluene SCHEMBL10908243 0.89 ALDH1A1 (0.71) ALDH1A1TSHRMAPK1TDP1CYP3A4
Hydrochloric Acid SCHEMBL1450346 0.87 ALDH1A1 (0.94) ALDH1A1TSHRMAPK1TDP1CYP3A4
SCHEMBL20169472 0.86 ALDH1A1 (0.58) ALDH1A1TSHRMAPK1TDP1CYP3A4
SCHEMBL10534118 0.86 ALDH1A1 (0.58) ALDH1A1TSHRMAPK1TDP1CYP3A4
SCHEMBL11019084 0.85 ALDH1A1 (0.71) ALDH1A1TSHRMAPK1TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3717457-A1 PROCESS FOR PREPARATION OF ENZALUTAMIDE USING NOVEL INTERMEDIATE Aarti Industries Limited (IN) 2020-10-07 EP claimed
EP-3717457-B1 PROCESS FOR PREPARATION OF ENZALUTAMIDE USING NOVEL INTERMEDIATE AARTI INDUSTRIES LTD (IN) 2023-06-21 EP disclosed
CN-110015952-B Diaryl methane compound and preparation method and application thereof 北京大学深圳研究生院 2022-08-19 CN disclosed
CN-105793778-A PHOTOSENSITIVE RESIN COMPOSITION AND PHOTOSENSITIVE RESIN LAMINATE 旭化成株式会社 2016-07-20 CN disclosed
CN-101910943-B Photosensitive resin laminate ASAHI KASEI E MATERIALS CORP 2015-03-25 CN disclosed
CN-104111584-A Photosensitive resin composition ASAHI KASEI E MATERIALS CORP 2014-10-22 CN disclosed
CN-102428406-B Photosensitive resin composition ASAHI KASEI E MATERIALS CORP 2014-09-03 CN disclosed
CN-102549498-B Photosensitive resin composition for resist material and photosensitive resin laminate ASAHI KASEI E MATERIALS CORP 2013-10-30 CN disclosed
CN-103282829-A Photosensitive resin composition ASAHI KASEI E MATERIALS CORP 2013-09-04 CN disclosed
CN-102007452-B Photosensitive resin composition and laminate thereof ASAHI KASEI E MATERIALS CORP 2012-10-31 CN disclosed
EP-0717402-A2 Optical recording elements having recording layers containing cationic azo dyes EASTMAN KODAK COMPANY (US) 1996-06-19 EP disclosed
US-5405843-A Anticancer drug potentiators MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1995-04-11 US disclosed
EP-0363212-B1 Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components MITSUI TOATSU CHEMICALS (JP) 1995-01-04 EP disclosed
US-5204348-A Quinoline derivatives MITSUI TOATSU CHEMICALS INC. (JP) 1993-04-20 US disclosed
US-5112817-A Anticancer Drug Potentiators MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1992-05-12 US disclosed
EP-0372778-A1 Photoinitiator Polychrome Corporation (US) 1990-06-13 EP disclosed
EP-0363212-A2 Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-04-11 EP disclosed
US-4459228-A POLYAMINES, COMPLEXING Gelsellschaft fur Biotechnologische Forschung (DE) 1984-07-10 US disclosed
EP-0049831-A2 Process for the precipitation of lignosulfonate from waste sulfite liquor Gesellschaft für Biotechnologische Forschung mbH (GBF) (DE) 1982-04-21 EP disclosed
US-4142898-A Imaging film of sensitizing layer upon UV-sensitive diazo layer ENERGY CONVERSION DEVICES, INC. (US) 1979-03-06 US disclosed