Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 10/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9940039 | 0.92 | PTGES (0.38) | PTGESENPP2TP53MAPTCNR1 | |
| SCHEMBL9939977 | 0.92 | PTGES (0.38) | PTGESENPP2TP53MAPTCNR1 | |
| SCHEMBL14238584 | 0.86 | HPGD (0.41) | PTGESENPP2TP53MAPTCNR1 | |
| SCHEMBL9941944 | 0.86 | SMO (0.44) | PTGESENPP2TP53MAPTCNR1 | |
| SCHEMBL9940038 | 0.83 | ALDH1A1 (0.40) | PTGESENPP2TP53MAPTLMNA | |
| SCHEMBL9939974 | 0.82 | PTGES (0.43) | PTGESENPP2CNR1 | |
| SCHEMBL9939771 | 0.81 | PTGES (0.47) | PTGESENPP2TP53MAPTLMNA | |
| SCHEMBL9939775 | 0.81 | DRD2 (0.40) | PTGESENPP2CNR1TRPV1 | |
| SCHEMBL9939834 | 0.80 | PTGES (0.38) | PTGESENPP2MAPTCNR1TRPV1 | |
| SCHEMBL9939776 | 0.80 | PTGES (0.38) | PTGESENPP2CNR1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466186-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-18 | — | — | US | disclosed |