SCHEMBL15034728

SCHEMBL15034728

CCc1nc(C(C)C)ncc1C

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NUDT1 P36639 1/20 0.33
APLNR P35414 1/20 0.31
TKT P29401 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24786389 0.82 TKT (0.36) NUDT1APLNRTKT
SCHEMBL19523168 0.78 PTGS1 (0.33)
SCHEMBL24943638 0.76 CRHR1 (0.34)
SCHEMBL12858177 0.74 NUDT1 (0.36) NUDT1
SCHEMBL12447891 0.74 APLNR (0.35) APLNRTKT
SCHEMBL14997542 0.72 APLNR (0.34) APLNRTKT
SCHEMBL13165162 0.72 NUDT1 (0.35) NUDT1
SCHEMBL15044977 0.72 NOS3 (0.37) APLNRTKT
SCHEMBL2625494 0.71 TKT (0.41) NUDT1APLNRTKT
SCHEMBL18031204 0.71 NUDT1 (0.59) NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11773091-B2 6-5 fused rings as C5a inhibitors CHEMOCENTRYX, INC. (US) 2023-10-03 US disclosed
US-9802904-B2 Inhibitors of the USP1/UAF1 deubiquitinase complex and uses thereof THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2017-10-31 US disclosed
WO-2013086208-A1 SUBSTITUTED PYRIMIDINONE-PHENYL-PYRIMIDINYL COMPOUNDS CONFLUENCE LIFE SCIENCES, INC. (US) 2013-06-13 WO disclosed
CN-1039645-C 1,3-(substd. thio) acetoxy Melbamycinum derivatives, their preparation method, and use in agricultural chemistry SANKYO CO (JP) 1998-09-02 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11773091-B2 6-5 fused rings as C5a inhibitors C5AR1, C5AR2, C3AR1 NUDT1 2157/4885APLNR 132/4885TKT 4508/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.