Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | PON1 | P27169 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29558862 | 0.85 | L3MBTL1 (0.44) | CYP1A2CYP2A6ALDH1A1TSHRCYP3A4 | |
| SCHEMBL2466440 | 0.85 | L3MBTL1 (0.44) | CYP1A2CYP2A6ALDH1A1TSHRCYP3A4 | |
| SCHEMBL8816153 | 0.81 | CYP1A2 (0.65) | CYP1A2CYP2A6DAOALDH1A1TSHR | |
| SCHEMBL9519292 | 0.79 | CYP1A2 (0.62) | CYP1A2CYP2A6DAOALDH1A1TSHR | |
| SCHEMBL7754391 | 0.79 | CYP1A2 (0.62) | CYP1A2CYP2A6DAOALDH1A1NPBWR1 | |
| SCHEMBL30975074 | 0.79 | CYP1A2 (0.62) | CYP1A2CYP2A6DAOALDH1A1TSHR | |
| SCHEMBL19676944 | 0.77 | CYP1A2 (0.59) | CYP1A2CYP2A6DAOALDH1A1NPBWR1 | |
| SCHEMBL2454747 | 0.77 | CYP1A2 (0.59) | CYP1A2CYP2A6DAOALDH1A1NPBWR1 | |
| SCHEMBL3914647 | 0.77 | CYP1A2 (0.59) | CYP1A2CYP2A6DAOALDH1A1TSHR | |
| SCHEMBL3078325 | 0.77 | CYP1A2 (0.59) | CYP1A2CYP2A6DAOALDH1A1NPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777411-A | Crosslinked methylene aromatic hydrocarbon high polymer and synthesis method thereof | 乐山师范学院 | 2024-03-29 | — | — | CN | claimed |
| CN-100596295-C | 1-methyl-4[4-(N,N-p-methylphenyl amido)styryl]naphthyl and method of manufacturing the same and application thereof | UNIV TIANJIN | 2010-03-31 | — | — | CN | claimed |
| CN-101108808-A | 1-methyl-4[4-(N,N-p-methylphenyl amido)styryl]naphthyl and method of manufacturing the same and application thereof | UNIV TIANJIN (CN) | 2008-01-23 | — | — | CN | claimed |
| US-4152352-A | PRODUCTION OF ARYLPYRUVIC ACIDS | RHONE-POULENC INDUSTRIES (FR) | 1979-05-01 | — | — | US | claimed |
| CN-121850824-A | Preparation method of 1, 4-dimethylnaphthalene | 湖北迪赛鸿宇新材料技术有限公司 | 2026-04-14 | — | — | CN | disclosed |
| CN-117777411-A | Crosslinked methylene aromatic hydrocarbon high polymer and synthesis method thereof | 乐山师范学院 | 2024-03-29 | — | — | CN | disclosed |
| US-9266848-B2 | 4-alkoxy-N-(2-hydroxycarbamoyl-2-piperidinyl-ethyl)-benzamide compounds as selective TACE-inhibitors for the treatment of inflammatory diseases | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2016-02-23 | — | — | US | disclosed |
| EP-2477969-B1 | 4-ALKOXY-N-(2-HYDROXYCARBAMOYL-2-PIPERIDINYL-ETHYL)-BENZAMIDE COMPOUNDS AS SELECTIVE TACE-INHIBITORS FOR THE TREATMENT OF INFLAMMATORY DISEASES. | GALDERMA RES & DEV (FR) | 2013-10-23 | — | — | EP | disclosed |
| US-8329727-B2 | Imidazo[4,5-c]pyridine compounds and methods of antiviral treatment | GILEAD SCIENCES, INC. (US) | 2012-12-11 | — | — | US | disclosed |
| US-20120226033-A1 | 4-ALKOXY-N- (2-HYDROXYCARBAMOYL-2-PIPERIDINYL-ETHYL) -BENZAMIDE COMPOUNDS AS SELECTIVE TACE-INHIBITORS FOR THE TREATMENT OF INFLAMMATORY DISEASES | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2012-09-06 | — | — | US | disclosed |
| EP-2477969-A1 | 4-ALKOXY-N- (2-HYDROXYCARBAMOYL-2-PIPERIDINYL-ETHYL) -BENZAMIDE COMPOUNDS AS SELECTIVE TACE-INHIBITORS FOR THE TREATMENT OF INFLAMMATORY DISEASES | Galderma Research & Development (FR) | 2012-07-25 | — | — | EP | disclosed |
| WO-2011033010-A1 | 4-ALKOXY-N- (2-HYDROXYCARBAMOYL-2-PIPERIDINYL-ETHYL) -BENZAMIDE COMPOUNDS AS SELECTIVE TACE-INHIBITORS FOR THE TREATMENT OF INFLAMMATORY DISEASES | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-03-24 | — | — | WO | disclosed |
| US-20070244148-A1 | Imidazo 4,5-C Pyridine Compounds and Methods of Antiviral Treatment | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2007-10-18 | — | — | US | disclosed |
| US-20070244148-A1 | Imidazo 4,5-C Pyridine Compounds and Methods of Antiviral Treatment | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2007-10-18 | — | — | US | disclosed |
| EP-1268494-A1 | SULFUR SUBSTITUTED ARYLDIFLUOROMETHYLPHOSPHONIC ACIDS AS PTP-1B INHIBITORS | Merck Frosst Canada & Co. (CA) | 2003-01-02 | — | — | EP | disclosed |
| US-6498151-B2 | PROTEIN TYROSINE PHOSPHATASES INHIBITORS, ESPECIALLY AS ANTIDIABETIC AGENTS | MERCK FROSST CANADA & CO. (CA) | 2002-12-24 | — | — | US | disclosed |
| US-20020091104-A1 | Aryldifluoromethylphosphonic acids with sulfur-containing substituents as PTP-1B inhibitors | MERCK FROSST CANADA LTD. (CA) | 2002-07-11 | — | — | US | disclosed |
| WO-2001070753-A1 | SULFUR SUBSTITUTED ARYLDIFLUOROMETHYLPHOSPHONIC ACIDS AS PTP-1B INHIBITORS | MERCK FROSST CANADA & CO. (CA) | 2001-09-27 | — | — | WO | disclosed |
| US-4576809-A | COBALT/II/COMPOUND, CARBON MONOXIDE, HYDROXIDE, SULFUR COMPOUND | RHONE-POULENC SPECIALITIES CHIMIQUES (FR) | 1986-03-18 | — | — | US | disclosed |
| US-4152352-A | PRODUCTION OF ARYLPYRUVIC ACIDS | RHONE-POULENC INDUSTRIES (FR) | 1979-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244148-A1 | Imidazo 4,5-C Pyridine Compounds and Methods of Antiviral Treatment | ZC3HAV1, TPMT, DPP4 | CYP1A2 336/4885CYP2A6 177/4885DAO 823/4885 |
| US-20120226033-A1 | 4-ALKOXY-N- (2-HYDROXYCARBAMOYL-2-PIPERIDINYL-ETHYL) -BENZAMIDE COMPOUNDS AS SELECTIVE TACE-INHIBITORS FOR THE TREATMENT OF INFLAMMATORY DISEASES | TPSAB1, CTSB, TPSB2 | CYP1A2 257/4885CYP2A6 826/4885DAO 668/4885 |
| US-20020091104-A1 | Aryldifluoromethylphosphonic acids with sulfur-containing substituents as PTP-1B inhibitors | PTPRF, PTPRS, PTPRO | CYP1A2 2543/4885CYP2A6 408/4885DAO 1023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.