Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tetraethylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetraethylene Glycol SCHEMBL321240 | 0.94 | MEN1 (0.52) | MEN1KMT2ATHRBHTTMAPT | |
| Di(Hydroxyethyl)Ether SCHEMBL3067562 | 0.91 | TSHR (0.50) | MEN1KMT2ATHRBHTTMAPT | |
| Di(Hydroxyethyl)Ether SCHEMBL27629577 | 0.89 | TSHR (0.48) | MEN1KMT2ATHRBHTTMAPT | |
| Triethylene Glycol SCHEMBL2967311 | 0.87 | MEN1 (0.50) | MEN1KMT2ATHRBHTTMAPT | |
| Triethylene Glycol SCHEMBL8013235 | 0.87 | MEN1 (0.61) | MEN1KMT2ATHRBHTTMAPT | |
| Tetraethylene Glycol SCHEMBL8850597 | 0.87 | MEN1 (0.61) | MEN1KMT2ATHRBHTTMAPT | |
| Propylene Glycol SCHEMBL8851429 | 0.87 | MEN1 (0.61) | MEN1KMT2ATHRBHTTMAPT | |
| Propylene Glycol SCHEMBL3359839 | 0.87 | MEN1 (0.61) | MEN1KMT2ATHRBHTTMAPT | |
| Triethylene Glycol SCHEMBL22077278 | 0.87 | MEN1 (0.61) | MEN1KMT2ATHRBHTTMAPT | |
| Triethylene Glycol SCHEMBL6869496 | 0.87 | MEN1 (0.61) | MEN1KMT2ATHRBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9000232-B2 | Extractive distillation of crude alcohol product | CELANESE INTERNATIONAL CORPORATION (US) | 2015-04-07 | — | — | US | claimed |
| US-9000235-B2 | Extractive distillation of crude alcohol product | CELANESE INTERNATIONAL CORPORATION (US) | 2015-04-07 | — | — | US | claimed |
| US-20140303407-A1 | Extractive Distillation of Crude Alcohol Product | CELANESE INTERNATIONAL CORPORATION (US) | 2014-10-09 | — | — | US | claimed |
| US-20120323050-A1 | Extractive Distillation of Crude Alcohol Product | CELANESE INTERNATIONAL CORPORATION (US) | 2012-12-20 | — | — | US | claimed |
| US-20120277463-A1 | Extractive Distillation of Crude Alcohol Product | CELANESE INTERNATIONAL CORPORATION (US) | 2012-11-01 | — | — | US | claimed |
| US-9670119-B2 | Process for producing ethanol using multiple beds each having different catalysts | CELANESE INTERNATIONAL CORPORATION (US) | 2017-06-06 | — | — | US | disclosed |
| EP-2531470-B1 | PROCESS FOR PRODUCING ETHANOL USING AN EXTRACTIVE DISTILLATION COLUMN | CELANESE INT CORP (US) | 2016-06-15 | — | — | EP | disclosed |
| US-9353034-B2 | Hydrogenation process with reduced residence time for vapor phase reactants | CELANESE INTERNATIONAL CORPORATION (US) | 2016-05-31 | — | — | US | disclosed |
| EP-2702023-B1 | REDUCTION OF ACID WITHIN COLUMN THROUGH ESTERIFICATION DURING THE PRODUCTION OF ALCOHOLS | CELANESE INT CORP (US) | 2016-03-09 | — | — | EP | disclosed |
| US-9272970-B2 | Hydrogenolysis of ethyl acetate in alcohol separation processes | CELANESE INTERNATIONAL CORPORATION (US) | 2016-03-01 | — | — | US | disclosed |
| EP-2702022-B1 | PROCESS FOR PRODUCING ETHANOL USING MULTIPLE BEDS EACH HAVING DIFFERENT CATALYSTS | CELANESE INT CORP (US) | 2015-12-09 | — | — | EP | disclosed |
| US-9150474-B2 | Reduction of acid within column through esterification during the production of alcohols | CELANESE INTERNATIONAL CORPORATION (US) | 2015-10-06 | — | — | US | disclosed |
| WO-2012006219-A2 | LIQUID ESTERIFICATION FOR THE PRODUCTION OF ALCOHOLS | CELANESE INTERNATIONAL CORPORATION (US) | 2012-01-12 | — | — | WO | disclosed |
| WO-2012006236-A1 | WEAK ACID RECOVERY SYSTEM FOR ETHANOL SEPARATION PROCESSES | CELANESE INTERNATIONAL CORPORATION (US) | 2012-01-12 | — | — | WO | disclosed |
| WO-2012006438-A2 | HYDROGENOLYSIS OF ETHYL ACETATE IN ALCOHOL SEPARATION PROCESSES | CELANESE INTERNATIONAL CORPORATION (US) | 2012-01-12 | — | — | WO | disclosed |
| US-20120010446-A1 | Hydrogenolysis of Ethyl Acetate in Alcohol Separation Processes | CELANESE INTERNATIONAL CORPORATION (US) | 2012-01-12 | — | — | US | disclosed |
| US-20110275864-A1 | PROCESS FOR PRODUCING ETHANOL USING AN EXTRACTIVE DISTILLATION COLUMN | CELANESE INTERNATIONAL CORPORATION (US) | 2011-11-10 | — | — | US | disclosed |
| WO-2011140457-A1 | PROCESS FOR RECOVERING ETHANOL PRODUCED BY HYDROGENATING ACETIC ACID COMPRISING WATER | CELANESE INTERNATIONAL CORPORATION (US) | 2011-11-10 | — | — | WO | disclosed |
| WO-2011097220-A2 | PROCESS FOR PRODUCING ETHANOL USING AN EXTRACTIVE DISTILLATION COLUMN | CELANESE INTERNATIONAL CORPORATION (US) | 2011-08-11 | — | — | WO | disclosed |
| US-4569726-A | USING AS EXTRACTIVE AGENT ETHYLENE OXIDE ADDUCT AND DIPROPYLENE GLYCOL, DIETHYLENE GLYCOL OR TRIETHYLENE GLYCOL | BERG LLOYD | 1986-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275864-A1 | PROCESS FOR PRODUCING ETHANOL USING AN EXTRACTIVE DISTILLATION COLUMN | ADH1C, ADH1A, ADH5 | MEN1 3871/4885KMT2A 3348/4885THRB 3952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.